Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | CTSD | P07339 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6693045 | 1.00 | MTNR1A (0.52) | MTNR1AMTNR1BALDH1A1POLBABCB1 | |
| SCHEMBL6693523 | 0.85 | MTNR1A (0.55) | MTNR1AMTNR1BALDH1A1POLBABCB1 | |
| SCHEMBL6693520 | 0.85 | MTNR1A (0.55) | MTNR1AMTNR1BALDH1A1POLBABCB1 | |
| SCHEMBL6690026 | 0.85 | MTNR1A (0.54) | MTNR1AMTNR1BALDH1A1POLBABCB1 | |
| SCHEMBL6690014 | 0.85 | MTNR1A (0.54) | MTNR1AMTNR1BALDH1A1POLBABCB1 | |
| SCHEMBL6689560 | 0.81 | FFAR4 (0.41) | ALDH1A1NPC1PKMRAB9ACSF1R | |
| SCHEMBL6689557 | 0.81 | FFAR4 (0.41) | ALDH1A1NPC1PKMRAB9ACSF1R | |
| SCHEMBL6689670 | 0.80 | MTNR1A (0.53) | MTNR1AMTNR1BALDH1A1POLBABCB1 | |
| SCHEMBL6689665 | 0.80 | MTNR1A (0.53) | MTNR1AMTNR1BALDH1A1POLBABCB1 | |
| SCHEMBL6686209 | 0.79 | PDCD1 (0.44) | ALDH1A1NPC1PKMRAB9AMRGPRX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087125-A1 | AMINO ACID DERIVATIVES AS INHIBITORS OF MAMMALIAN SODIUM CHANNELS | IONIX PHARMACEUTICALS LIMITED (GB) | 2004-10-14 | — | — | WO | disclosed |