Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | STAT3 | P40763 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.30 |
| ▸ | FNTB | P49356 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lyral SCHEMBL5986927 | 0.87 | MEN1 (0.44) | MEN1KMT2ACYP3A4ALOX15STAT3 | |
| Lyral SCHEMBL26622234 | 0.81 | ALDH1A1 (0.39) | MEN1KMT2ACYP3A4ALOX15STAT3 | |
| Lyral SCHEMBL30754376 | 0.79 | CES2 (0.39) | MEN1KMT2ACYP3A4ALOX15STAT3 | |
| Lyral SCHEMBL20605413 | 0.79 | CES2 (0.39) | MEN1KMT2ACYP3A4ALOX15STAT3 | |
| Lyral SCHEMBL112060 | 0.79 | CES2 (0.39) | MEN1KMT2ACYP3A4ALOX15STAT3 | |
| Lyral SCHEMBL28150914 | 0.78 | CES2 (0.38) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL214415 | 0.76 | ALDH1A1 (0.53) | MEN1KMT2ACYP3A4ALOX15STAT3 | |
| SCHEMBL29626008 | 0.76 | ALDH1A1 (0.53) | MEN1KMT2ACYP3A4ALOX15STAT3 | |
| SCHEMBL19717960 | 0.76 | ALDH1A1 (0.53) | MEN1KMT2ACYP3A4ALOX15STAT3 | |
| SCHEMBL5019006 | 0.71 | CES2 (0.41) | MEN1KMT2ACYP3A4ALOX15STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004052330-A1 | SKIN LIGHTENING DERIVATIVES OF DI-THIANE RESORCINOL, COMPOSITIONS AND METHODS | UNILEVER PLC (GB) | 2004-06-24 | — | — | WO | disclosed |
| WO-2004052329-A1 | DI-SUBSTITUTED RESORCINOLS AS SKIN LIGHTENING AGENTS | UNILEVER PLC (GB) | 2004-06-24 | — | — | WO | disclosed |