Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperidine SCHEMBL28265006 | 0.83 | NPC1 (0.57) | KMT2AALDH1A1GFERTDP1L3MBTL1 | |
| SCHEMBL79657 | 0.83 | TDP1 (0.67) | KMT2AALDH1A1TDP1L3MBTL1MAPT | |
| SCHEMBL27719889 | 0.81 | TDP1 (0.64) | KMT2AALDH1A1TDP1L3MBTL1MAPT | |
| Propiophenone SCHEMBL27835084 | 0.81 | MAPT (0.55) | KMT2AALDH1A1GFERTDP1L3MBTL1 | |
| Propiophenone SCHEMBL28050246 | 0.79 | MAPT (0.53) | KMT2AALDH1A1GFERTDP1L3MBTL1 | |
| Benzophenone SCHEMBL3444030 | 0.77 | ALDH1A1 (0.61) | KMT2AALDH1A1TDP1L3MBTL1MAPT | |
| Benzoic Acid SCHEMBL1716154 | 0.77 | TSHR (0.61) | KMT2AALDH1A1HPGDCES1SMN1; SMN2 | |
| Benzoic Acid SCHEMBL1249244 | 0.77 | TSHR (0.61) | KMT2AALDH1A1HPGDCES1SMN1; SMN2 | |
| Benzophenone SCHEMBL27842783 | 0.77 | ALDH1A1 (0.50) | KMT2AALDH1A1TDP1L3MBTL1MAPT | |
| Piperidine SCHEMBL28050617 | 0.77 | HPGD (0.50) | KMT2AALDH1A1TDP1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004285072-A | NEW PIPERIDINE DERIVATIVES | MERRELL PHARMACEUTICALS INC | 2004-10-14 | — | — | JP | disclosed |