SCHEMBL6693440

SCHEMBL6693440

CCCCC(CCCC(COc1ccc(O)cc1)C(C)(C)C)C(C)(C)C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 4/20 0.49
NR5A1 Q13285 1/20 0.49
SLC6A2 P23975 3/20 0.39
PTGS1 P23219 2/20 0.39
LMNA P02545 3/20 0.38
HSD17B10 Q99714 2/20 0.38
ABCG2 Q9UNQ0 1/20 0.37
S1PR1 P21453 3/20 0.37
ESR1 P03372 4/20 0.37
ADRA2A P08913 2/20 0.37
ADORA3 P0DMS8 2/20 0.37
TACR2 P21452 2/20 0.37
SLC6A4 P31645 2/20 0.37
SLC6A3 Q01959 2/20 0.37
ADRB3 P13945 2/20 0.37
KDM4E B2RXH2 2/20 0.37
ALDH1A1 P00352 1/20 0.37
SHBG P04278 1/20 0.37
TP53 P04637 1/20 0.37
CYP3A4 P08684 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL808463 0.91 NR5A1 (0.57) LTA4HNR5A1SLC6A2PTGS1LMNA
SCHEMBL5634322 0.91 NR5A1 (0.57) LTA4HNR5A1SLC6A2PTGS1LMNA
SCHEMBL27715462 0.77 ESR1 (0.47) SLC6A2PTGS1LMNAHSD17B10ESR1
SCHEMBL7782844 0.76 LTA4H (0.56) LTA4HNR5A1SLC6A2PTGS1LMNA
SCHEMBL2045373 0.75 LTA4H (0.54) LTA4HNR5A1SLC6A2PTGS1LMNA
SCHEMBL9502936 0.75 LTA4H (0.54) LTA4HNR5A1SLC6A2PTGS1LMNA
SCHEMBL9624184 0.75 LTA4H (0.58) LTA4HNR5A1ABCG2ESR1ADRB3
SCHEMBL8374322 0.73 LTA4H (0.57) LTA4HNR5A1ABCG2ESR1ADRB3
SCHEMBL8674114 0.72 ESR1 (0.53) NR5A1SLC6A2PTGS1LMNAHSD17B10
SCHEMBL105327 0.72 ESR1 (0.53) NR5A1SLC6A2PTGS1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0987295-B1 Combination of an organothio compound and a zinc mercapto ester as heat stabilizer in PVC processing MORTON INT INC (US) 2004-07-21 EP disclosed
US-6462116-B2 POLYVINYL CHLORIDE(PVC), OR OTHER HALOPOLYMERS; 2-MERCAPTOETHANOL AND ZINC BIS(2-ETHYLHEXYLTHIOGLYCOLATE) FOR EXAMPLE; ELIMINATES ZINC BURN DURING PROCESSING MORTON INTERNATIONAL, INC. 2002-10-08 US disclosed
US-20010036987-A1 Combination of an organothio compound and a zinc mercapto ester as a heat stabilizer in PVC processing MORTON INTERNATIONAL, INC. 2001-11-01 US disclosed
EP-0623648-B1 A combination heat stabilizer/lubricant for PVC processing and method for producing the same MORTON INT INC (US) 2000-07-05 EP disclosed
EP-0987295-A1 Combination of an organothio compound and a zinc mercapto ester as heat stabilizer in PVC processing MORTON INTERNATIONAL, INC. (US) 2000-03-22 EP disclosed
EP-0623649-B1 Polyol esters of zinc mercaptoacids as heat stabilizers for PVC processing MORTON INT INC (US) 1999-07-21 EP disclosed
US-5536767-A Polyol esters of zinc mercaptoacids as heat stabilizers for PVC processing MORTON INTERNATIONAL, INC. (US) 1996-07-16 US disclosed
US-5532303-A HEAT RESISTANT POLYMER COMPOSITIONS WITH MERCAPTIDES MORTON INTERNATIONAL, INC. (US) 1996-07-02 US disclosed
US-5444111-A Heat resistance during early stages of extrusion MORTON INTERNATIONAL, INC. (US) 1995-08-22 US disclosed
EP-0623648-A1 A combination heat stabilizer/lubricant for PVC processing and method for producing the same MORTON INTERNATIONAL, INC. (US) 1994-11-09 EP disclosed
US-5332772-A Zinc mercaptoester, paraffin wax, calcium stearate MORTON INTERNATIONAL, INC. (US) 1994-07-26 US disclosed
EP-0068640-B1 STABILISING MATERIALS FOR HALOGEN-CONTAINING POLYMERS AND POLYMER COMPOSITIONS CONTAINING THE SAME MORTON THIOKOL, INC. (US) 1986-11-05 EP disclosed
US-4515916-A HEAT RESISTANCE MORTON THIOKOL INC. (US) 1985-05-07 US disclosed
US-4391757-A Organic antimony containing stabilizer compositions for halogenated polymers CARSTAB CORPORATION (US) 1983-07-05 US disclosed
EP-0068640-A1 Stabilising materials for halogen-containing polymers and polymer compositions containing the same MORTON THIOKOL, INC. (US) 1983-01-05 EP disclosed
US-4366277-A STABILIZERS FOR POLYMERS; PHOTOSTABILITY; HEAT RESISTANCE CARSTAB CORPORATION (US) 1982-12-28 US disclosed
US-4358555-A HEAT TESISTANCE CARSTAB CORPORATION (US) 1982-11-09 US disclosed
US-4356279-A HEAT AND LIGHT STABILIZERS CARSTAB CORPORATION (US) 1982-10-26 US disclosed
EP-0033663-A1 2,2,6,6-Tetramethyl-4-piperidyl - substituted heterocyclic ring compounds, a method for their preparation and polymers containing the same CARSTAB CORPORATION (US) 1981-08-12 EP disclosed
US-4021407-A DISCOLORATION INHIBITION CINCINNATI MILACRON, INC. (US) 1977-05-03 US disclosed