SCHEMBL808463

SCHEMBL808463

CCCCCCCCCCC(COc1ccc(O)cc1)C(C)(C)C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR5A1 Q13285 1/20 0.57
LTA4H P09960 4/20 0.50
ESR1 P03372 5/20 0.44
SLC6A2 P23975 3/20 0.44
ADRA2A P08913 2/20 0.44
ADORA3 P0DMS8 2/20 0.44
TACR2 P21452 2/20 0.44
SLC6A4 P31645 2/20 0.44
SLC6A3 Q01959 2/20 0.44
PTGS1 P23219 2/20 0.44
LMNA P02545 2/20 0.44
TP53 P04637 2/20 0.44
HSD17B10 Q99714 2/20 0.44
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44
SHBG P04278 1/20 0.44
CYP3A4 P08684 1/20 0.44
HSPD1 P10809 1/20 0.44
ADRB3 P13945 1/20 0.44
HTR2C P28335 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5634322 1.00 NR5A1 (0.57) NR5A1LTA4HESR1SLC6A2ADRA2A
SCHEMBL6693440 0.91 LTA4H (0.49) NR5A1LTA4HESR1SLC6A2ADRA2A
SCHEMBL8374339 0.79 NR5A1 (0.60) NR5A1LTA4HESR1SLC6A2ADRA2A
SCHEMBL9629026 0.78 NR5A1 (0.58) NR5A1LTA4HESR1SLC6A2ADRA2A
SCHEMBL9629030 0.78 NR5A1 (0.58) NR5A1LTA4HESR1SLC6A2ADRA2A
SCHEMBL6441845 0.77 LMNA (0.40) ADRA2ASLC6A3LMNACYP3A4CHRM2
SCHEMBL6346051 0.77 LMNA (0.40) ADRA2ASLC6A3LMNACYP3A4CHRM2
SCHEMBL688630 0.77 ESR1 (0.56) NR5A1ESR1SLC6A2ADRA2AADORA3
SCHEMBL1240638 0.77 ESR1 (0.56) NR5A1ESR1SLC6A2ADRA2AADORA3
SCHEMBL106676 0.77 ESR1 (0.56) NR5A1ESR1SLC6A2ADRA2AADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1652881-B1 Thermal stabilizer compositions for halogen-containing vinyl polymers ROHM & HAAS (US) 2011-11-23 EP disclosed
US-7488433-B2 Thermal stabilizer compositions for halogen-containing vinyl polymers ROHM AND HAAS COMPANY (US) 2009-02-10 US disclosed
EP-1621576-B1 Thermal stabilizer compositions for halogen-containing vinyl polymers ROHM & HAAS (US) 2007-02-14 EP disclosed
US-7109261-B2 Latent mercaptans as multi-functional additives for halogen-containing polymer compositions ROHM AND HAAS COMPANY (US) 2006-09-19 US disclosed
US-7105109-B2 Latent mercaptans as stabilizers for halogen-containing polymer compositions ROHM AND HAAS COMPANY (US) 2006-09-12 US disclosed
EP-1652881-A1 Thermal stabilizer compositions for halogen-containing vinyl polymers Rohm and Haas Company (US) 2006-05-03 EP disclosed
US-20060089436-A1 Thermal stabilizer compositions for halogen-containing vinyl polymers AUSTEN STEVEN C 2006-04-27 US disclosed
US-20060079611-A1 Thermal stabilizer compositions for halogen-containing vinyl polymers AUSTEN STEVEN C 2006-04-13 US disclosed
EP-1645592-A1 Thermal stabilizer compositions for halogen-containing vinyl polymers Rohm and Haas Company (US) 2006-04-12 EP disclosed
US-7025904-B2 Method for improving adhesion of water-based inks to halogen-containing resin articles ROHM AND HAAS COMPANY (US) 2006-04-11 US disclosed
US-6232380-B1 HEAT RESISTANCE, PHOTOSTABILITY, WEATHERPROOFING MORTON INTERNATIONAL INC. 2001-05-15 US disclosed
CN-1275591-A Process for improving adhesion force of water base ink to halogen-containing resin products ROHM & HAAS (US) 2000-12-06 CN disclosed
EP-1055704-A2 Method for improving adhesion of water based inks to halogen containing resin articles ROHM AND HAAS COMPANY (US) 2000-11-29 EP disclosed
EP-0742259-B1 Latent mercaptans as multi-functional additives for halogen-containing polymer compositions MORTON INT INC (US) 2000-10-18 EP disclosed
EP-1004624-A1 Latent mercaptan stabilizers for improved weatherability of clear halogen-containing polymer compositions MORTON INTERNATIONAL, INC. (US) 2000-05-31 EP disclosed
EP-0994148-A1 A pleasantly fragrant process for stabilizing halogen-containing polymers MORTON INTERNATIONAL, INC. (US) 2000-04-19 EP disclosed
EP-0945484-A1 Synergistic blend of a metal-based stabilizer or Lewis acid and a free mercaptan for enhanced PVC stabilization MORTON INTERNATIONAL, INC. (US) 1999-09-29 EP disclosed
EP-0945485-A1 A latent mercaptan as a heat stabilizer MORTON INTERNATIONAL, INC. (US) 1999-09-29 EP disclosed
EP-0890608-A2 A latent mercaptan as a heat stabilizer MORTON INTERNATIONAL, INC. (US) 1999-01-13 EP disclosed
EP-0742259-A1 Latent mercaptans as multi-functional additives for halogen-containing polymer compositions MORTON INTERNATIONAL, INC. (US) 1996-11-13 EP disclosed