Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.53 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22492359 | 0.90 | CYP1A2 (0.76) | CYP1A2CYP3A4CYP2C19ALDH1A1LMNA | |
| SCHEMBL29801772 | 0.90 | CYP1A2 (0.76) | CYP1A2CYP3A4CYP2C19ALDH1A1LMNA | |
| SCHEMBL7258392 | 0.90 | CYP1A2 (0.76) | CYP1A2CYP3A4CYP2C19ALDH1A1LMNA | |
| SCHEMBL1430430 | 0.88 | CYP1A2 (0.63) | CYP1A2CYP3A4CYP2C19ALDH1A1LMNA | |
| SCHEMBL3274638 | 0.86 | CYP1A2 (0.60) | CYP1A2CYP3A4CYP2C19ALDH1A1LMNA | |
| SCHEMBL29376920 | 0.85 | CYP1A2 (0.66) | CYP1A2CYP3A4CYP2C19ALDH1A1CLEC4M | |
| SCHEMBL9635290 | 0.85 | CYP1A2 (0.66) | CYP1A2CYP3A4CYP2C19ALDH1A1CLEC4M | |
| SCHEMBL21591836 | 0.84 | CYP1A2 (0.58) | CYP1A2CYP3A4CYP2C19ALDH1A1LMNA | |
| SCHEMBL4650007 | 0.83 | CYP1A2 (0.52) | CYP1A2CYP3A4CYP2C19ALDH1A1LMNA | |
| SCHEMBL11235716 | 0.83 | CYP1A2 (0.63) | CYP1A2CYP3A4CYP2C19ALDH1A1CLEC4M |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170281649-A1 | COMPOUNDS AND THERAPEUTIC USES | UNITY BIOTECHNOLOGY, INC. | 2017-10-05 | — | — | US | disclosed |
| US-20170281649-A1 | COMPOUNDS AND THERAPEUTIC USES | UNITY BIOTECHNOLOGY, INC. | 2017-10-05 | — | — | US | disclosed |
| WO-2004101589-A1 | NOVEL 14 AND 15 MEMBERED-RING COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2004-11-25 | — | — | WO | disclosed |
| US-4914110-A | BACTERICIDES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (FR) | 1990-04-03 | — | — | US | disclosed |
| US-4914110-A | BACTERICIDES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (FR) | 1990-04-03 | — | — | US | disclosed |
| US-4782068-A | BACTERICIDES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (FR) | 1988-11-01 | — | — | US | disclosed |
| US-4782068-A | BACTERICIDES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (FR) | 1988-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170281649-A1 | COMPOUNDS AND THERAPEUTIC USES | TP53, NQO1, SHMT2 | CYP1A2 4049/4885CYP3A4 4584/4885CYP2C19 4777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.