Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.76 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.76 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.53 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6693441 | 0.90 | CYP1A2 (0.64) | CYP1A2CYP3A4CYP2C19CLEC4MKDM4E | |
| SCHEMBL1430430 | 0.88 | CYP1A2 (0.63) | CYP1A2CYP3A4CYP2C19CLEC4MKDM4E | |
| SCHEMBL3274638 | 0.86 | CYP1A2 (0.60) | CYP1A2CYP3A4CYP2C19CLEC4MKDM4E | |
| SCHEMBL29376920 | 0.85 | CYP1A2 (0.66) | CYP1A2CYP3A4CYP2C19CLEC4MKDM4E | |
| SCHEMBL9635290 | 0.85 | CYP1A2 (0.66) | CYP1A2CYP3A4CYP2C19CLEC4MKDM4E | |
| SCHEMBL21591836 | 0.84 | CYP1A2 (0.58) | CYP1A2CYP3A4CYP2C19CLEC4MKDM4E | |
| SCHEMBL11235716 | 0.83 | CYP1A2 (0.63) | CYP1A2CYP3A4CYP2C19CLEC4MKDM4E | |
| SCHEMBL19971590 | 0.82 | CYP1A2 (0.62) | CYP1A2CYP3A4CYP2C19CLEC4MKDM4E | |
| SCHEMBL30540821 | 0.82 | CYP1A2 (0.62) | CYP1A2CYP3A4CYP2C19CLEC4MKDM4E | |
| SCHEMBL1126279 | 0.82 | CLEC4M (0.78) | CYP1A2CYP3A4CYP2C19CLEC4MKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003089437-A1 | A TRIFLUOROACETIC ACID PROCESS TO PREPARE [2,3-B]PYRIDINE INTERMEDIATES | PHARMACIA & UPJOHN COMPANY (US) | 2003-10-30 | — | — | WO | claimed |