Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | OXTR | P30559 | 10/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 8/20 | 0.37 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6682055 | 0.90 | PTGS1 (0.42) | PTGS1PTGS2OXTRAVPR1AAVPR2 | |
| SCHEMBL6687338 | 0.90 | PTGS1 (0.42) | PTGS1PTGS2PDE4DOXTRAVPR1A | |
| SCHEMBL6682526 | 0.87 | PTGS1 (0.40) | PTGS1PTGS2OXTRAVPR1AAVPR2 | |
| SCHEMBL6682120 | 0.87 | PTGS1 (0.40) | PTGS1PTGS2OXTRAVPR1AAVPR2 | |
| SCHEMBL6682517 | 0.83 | PTGS1 (0.41) | PTGS1PTGS2OXTRAVPR1AAVPR2 | |
| SCHEMBL6687070 | 0.81 | GRIA2 (0.36) | PTGS1PTGS2MALT1OXTRAVPR1A | |
| SCHEMBL6682093 | 0.80 | MALT1 (0.41) | PTGS1PTGS2PDE4DMALT1MEN1 | |
| SCHEMBL6132456 | 0.78 | PTGS2 (0.67) | PTGS1PTGS2PDE4DMALT1 | |
| SCHEMBL6681645 | 0.78 | PTGS1 (0.40) | PTGS1PTGS2MALT1OXTRAVPR1A | |
| SCHEMBL6681046 | 0.73 | PTGS2 (0.60) | PTGS1PTGS2PDE4DMALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004060367-A1 | IMIDAZOLE AND TRIAZOLE DERIVATIVES USEFUL AS SELECTIVE COX-1 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-22 | — | — | WO | disclosed |