Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | OXTR | P30559 | 3/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | GPR183 | P32249 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132556 | 0.89 | PTGS2 (0.53) | PTGS1PTGS2MALT1OXTRAVPR2 | |
| SCHEMBL6135189 | 0.81 | PTGS2 (0.53) | PTGS1PTGS2MALT1OXTRCYP2A6 | |
| SCHEMBL6687139 | 0.80 | MEN1 (0.48) | PTGS1PTGS2OXTRAVPR2AVPR1A | |
| SCHEMBL6693458 | 0.78 | PTGS1 (0.42) | PTGS1PTGS2MALT1OXTRAVPR2 | |
| SCHEMBL6680327 | 0.76 | PTGS1 (0.45) | PTGS1PTGS2OXTRAVPR2AVPR1A | |
| SCHEMBL6686662 | 0.75 | PTGS1 (0.47) | PTGS1PTGS2MALT1OXTRAVPR2 | |
| SCHEMBL4028727 | 0.74 | PTGS2 (0.69) | PTGS1PTGS2MALT1 | |
| SCHEMBL5782756 | 0.73 | SMN1; SMN2 (0.51) | PTGS2MALT1MEN1KMT2AMAPT | |
| SCHEMBL5781861 | 0.72 | L3MBTL1 (0.44) | PTGS2MALT1MEN1KMT2AMAPT | |
| SCHEMBL6687276 | 0.72 | L3MBTL1 (0.42) | PTGS1PTGS2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004060367-A1 | IMIDAZOLE AND TRIAZOLE DERIVATIVES USEFUL AS SELECTIVE COX-1 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-22 | — | — | WO | disclosed |