Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 7/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6617647 | 0.91 | KCNH2 (0.43) | KCNH2MAOASIGMAR1 | |
| SCHEMBL6620288 | 0.91 | MAOA (0.51) | KCNH2MAOASIGMAR1 | |
| SCHEMBL6766942 | 0.89 | KCNH2 (0.44) | KCNH2MAOASIGMAR1 | |
| SCHEMBL6607680 | 0.87 | MAOA (0.54) | KCNH2MAOASIGMAR1 | |
| SCHEMBL6621257 | 0.87 | KCNH2 (0.46) | KCNH2MAOASIGMAR1 | |
| SCHEMBL6606802 | 0.85 | SIGMAR1 (0.41) | KCNH2MAOASIGMAR1 | |
| SCHEMBL6626227 | 0.85 | KCNH2 (0.43) | KCNH2MAOASIGMAR1 | |
| SCHEMBL6620710 | 0.85 | MAOA (0.51) | KCNH2MAOASIGMAR1 | |
| SCHEMBL6621493 | 0.84 | KCNH2 (0.43) | KCNH2MAOASIGMAR1 | |
| SCHEMBL6609268 | 0.83 | KCNH2 (0.43) | KCNH2MAOASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448536-A1 | CYCLOPROPYL-CONTAINING OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF | Merck & Co., Inc. (US) | 2004-08-25 | — | — | EP | claimed |
| WO-2003048136-A1 | CYCLOPROPYL HEXANE CONTAINING OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF | MERCK & CO., INC. (US) | 2003-06-12 | — | — | WO | claimed |