⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21594323 | 0.80 | LMNA (0.58) | — | |
| SCHEMBL19205218 | 0.75 | LMNA (0.40) | — | |
| SCHEMBL14181973 | 0.75 | LMNA (0.36) | — | |
| SCHEMBL23564419 | 0.73 | LMNA (0.36) | — | |
| SCHEMBL15750870 | 0.73 | LMNA (0.40) | — | |
| SCHEMBL28113863 | 0.73 | — | — | |
| SCHEMBL6053318 | 0.71 | LMNA (0.48) | — | |
| SCHEMBL23687902 | 0.71 | ALDH1A1 (0.30) | — | |
| SCHEMBL1258047 | 0.67 | — | — | |
| SCHEMBL16845318 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018309-A1 | SILICONE HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2024-01-18 | — | — | US | disclosed |
| US-11802182-B2 | Silicone hydrogel contact lenses | ALCON INC. (CH) | 2023-10-31 | — | — | US | disclosed |
| US-11365288-B2 | Silicone hydrogel contact lenses | ALCON INC. (CH) | 2022-06-21 | — | — | US | disclosed |
| US-20210009762-A1 | SILICONE HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2021-01-14 | — | — | US | disclosed |
| US-20210009743-A1 | HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF | ALCON INC. (CH) | 2021-01-14 | — | — | US | disclosed |
| US-10875967-B2 | Silicone hydrogel contact lenses | ALCON INC. (CH) | 2020-12-29 | — | — | US | disclosed |
| US-10870722-B2 | Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof | ALCON INC. (CH) | 2020-12-22 | — | — | US | disclosed |
| US-20190177460-A1 | HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF | ALCON INC. (CH) | 2019-06-13 | — | — | US | disclosed |
| US-10246543-B2 | Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof | NOVARTIS AG (CH) | 2019-04-02 | — | — | US | disclosed |
| US-20170166673-A1 | HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF | ALCON INC. (CH) | 2017-06-15 | — | — | US | disclosed |
| US-8956646-B2 | Zwitterionic lipids | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-02-17 | — | — | US | disclosed |
| US-20130216607-A1 | ZWITTERIONIC LIPIDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-08-22 | — | — | US | disclosed |
| WO-2012024233-A2 | ZWITTERIONIC LIPIDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-02-23 | — | — | WO | disclosed |
| EP-0109255-A2 | Glycerol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1984-05-23 | — | — | EP | disclosed |