SCHEMBL6693531

SCHEMBL6693531

Cc1ccc(OP(=S)(S)Sc2ccc(C)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.44
TSHR P16473 2/20 0.44
ACHE P22303 1/20 0.35
LMNA P02545 4/20 0.34
MAPT P10636 4/20 0.34
HPGD P15428 2/20 0.34
ALDH1A1 P00352 4/20 0.33
HSD17B10 Q99714 2/20 0.33
MEN1 O00255 4/20 0.32
KMT2A Q03164 4/20 0.32
TEAD4 Q15561 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
TP53 P04637 1/20 0.31
THRB P10828 1/20 0.31
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
POLB P06746 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1048938 0.82 CYP3A4 (0.48) CYP3A4TSHRACHELMNAMAPT
SCHEMBL6696442 0.81 CYP3A4 (0.47) CYP3A4TSHRACHELMNAMAPT
SCHEMBL1691991 0.78 TSHR (0.44) CYP3A4TSHRACHELMNAMAPT
SCHEMBL3072512 0.77 SRC (0.38) TSHRMAPTHPGDHSD17B10MEN1
Ammonia Solution, Strong SCHEMBL15546521 0.76 TSHR (0.42) CYP3A4TSHRACHELMNAMAPT
SCHEMBL10772624 0.76 CYP3A4 (0.42) CYP3A4TSHRACHELMNAMAPT
SCHEMBL1691989 0.76 CYP3A4 (0.54) CYP3A4TSHRACHELMNAMAPT
SCHEMBL1973376 0.76 ACHE (0.38) TSHRACHELMNAMAPTHPGD
SCHEMBL6692402 0.76 CYP3A4 (0.54) CYP3A4TSHRACHELMNAMAPT
SCHEMBL258632 0.75 CYP3A4 (0.58) CYP3A4TSHRACHELMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040204325-A1 Transmission fluid compositions for automobiles NIPPON OIL CORPORATION 2004-10-14 US disclosed
US-20040192562-A1 Lubricating oil composition NIPPON OIL CORPORATION 2004-09-30 US disclosed