SCHEMBL1973376

SCHEMBL1973376

Cc1ccc(SP(=S)(S)Sc2ccc(C)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 4/20 0.38
TDP1 Q9NUW8 3/20 0.38
DNMT1 P26358 1/20 0.34
ALDH1A1 P00352 3/20 0.32
IDO1 P14902 1/20 0.32
CYP2A6 P11509 1/20 0.32
MAPT P10636 2/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
HKDC1 Q2TB90 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
HPGD P15428 2/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
MLYCD O95822 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27414786 0.90 ALDH1A1 (0.50) ACHETDP1ALDH1A1CYP2A6MEN1
SCHEMBL8467881 0.82 LMNA (0.37) ACHETDP1DNMT1ALDH1A1IDO1
SCHEMBL1975999 0.80 ACHE (0.42) ACHETDP1DNMT1ALDH1A1CYP2A6
SCHEMBL11693774 0.76 ACHE (0.38) ACHETDP1DNMT1ALDH1A1CYP2A6
SCHEMBL8467854 0.76 LMNA (0.39) ACHETDP1DNMT1ALDH1A1CYP2A6
SCHEMBL10874516 0.76 ACHE (0.38) ACHETDP1DNMT1ALDH1A1CYP2A6
SCHEMBL869949 0.76 LMNA (0.39) ACHETDP1DNMT1ALDH1A1CYP2A6
SCHEMBL6693531 0.76 CYP3A4 (0.44) ACHETDP1ALDH1A1MAPTMEN1
SCHEMBL1975625 0.75 MAPT (0.41) ALDH1A1MAPTHPGDMAPK1HSD17B10
SCHEMBL1048938 0.71 CYP3A4 (0.48) ACHETDP1ALDH1A1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1816183-B1 DRIVING FORCE TRANSMITTING SYSTEM AND LUBRICANT COMPOSITION FOR THIS SYSTEM NIPPON OIL CORP (JP) 2011-06-22 EP disclosed
US-20080146474-A1 Lubricant Composition and Driving Force Transmitting System Using Same JTEKT CORPORATION (JP) 2008-06-19 US disclosed
EP-1816183-A1 LUBRICANT COMPOSITION AND DRIVING FORCE TRANSMITTING SYSTEM USING SAME Nippon Oil Corporation (JP) 2007-08-08 EP disclosed
US-5942470-A OIL SOLUBLE SULFUR CONTAINING PRESSURE AND ANTI-WEAR AGENT, AMINE SALT OF PHOSPHORUS ESTER, SUCCINIMIDE, AND ASHLESS DISPERSANTS ETHYL PETROLEUM ADDITIVES, INC. (US) 1999-08-24 US disclosed
EP-0459656-B1 Lubricant compositions ETHYL PETROLEUM ADDITIVES INC (US) 1995-09-20 EP disclosed
EP-0459656-A1 Lubricant compositions ETHYL PETROLEUM ADDITIVES, INC. (US) 1991-12-04 EP disclosed