Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 13/20 | 0.49 |
| ▸ | CTSL | P07711 | 9/20 | 0.41 |
| ▸ | CTSK | P43235 | 4/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | CLK1 | P49759 | 2/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6694447 | 0.91 | CTSS (0.52) | CTSSCTSLCTSKNPC1ALDH1A1 | |
| SCHEMBL6690052 | 0.81 | CTSS (0.43) | CTSSCTSLCTSKCASP3SENP8 | |
| SCHEMBL5357583 | 0.80 | CTSS (0.75) | CTSSCTSLCTSK | |
| SCHEMBL5357576 | 0.80 | CTSS (0.75) | CTSSCTSLCTSK | |
| SCHEMBL6690808 | 0.79 | CTSS (0.65) | CTSSCTSLCTSK | |
| SCHEMBL6698597 | 0.77 | CTSS (0.45) | CTSSCTSLCTSKNPC1ALDH1A1 | |
| SCHEMBL6693906 | 0.77 | CTSS (0.68) | CTSSCTSLCTSK | |
| SCHEMBL6698404 | 0.76 | CTSS (0.69) | CTSSCTSLCTSK | |
| SCHEMBL5359735 | 0.73 | CTSS (0.69) | CTSSCTSLCTSKCASP3SENP8 | |
| SCHEMBL5359739 | 0.73 | CTSS (0.69) | CTSSCTSLCTSKCASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004112709-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-12-29 | — | — | WO | claimed |