Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 20/20 | 0.68 |
| ▸ | CTSL | P07711 | 12/20 | 0.54 |
| ▸ | CTSK | P43235 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6698404 | 0.92 | CTSS (0.69) | CTSSCTSLCTSK | |
| SCHEMBL6694447 | 0.86 | CTSS (0.52) | CTSSCTSLCTSK | |
| SCHEMBL6698372 | 0.84 | CTSS (0.57) | CTSSCTSLCTSK | |
| SCHEMBL6690808 | 0.82 | CTSS (0.65) | CTSSCTSLCTSK | |
| SCHEMBL5357934 | 0.81 | CTSS (1.00) | CTSSCTSLCTSK | |
| SCHEMBL5357938 | 0.81 | CTSS (1.00) | CTSSCTSLCTSK | |
| SCHEMBL6692798 | 0.81 | CTSS (0.62) | CTSSCTSLCTSK | |
| SCHEMBL6693537 | 0.77 | CTSS (0.49) | CTSSCTSLCTSK | |
| SCHEMBL6697383 | 0.74 | CTSS (0.46) | CTSSCTSLCTSK | |
| SCHEMBL6689105 | 0.74 | CTSS (0.66) | CTSSCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004112709-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-12-29 | — | — | WO | disclosed |