Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GALK1 | P51570 | 1/20 | 0.36 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6694731 | 0.89 | MAPT (0.40) | ALDH1A1CYP1A2CYP2C19MAPTHPGD | |
| SCHEMBL6695155 | 0.83 | ALDH1A1 (0.32) | ALDH1A1CYP1A2CYP2C19MAPTHPGD | |
| SCHEMBL6694427 | 0.81 | ALDH1A1 (0.34) | ALDH1A1CYP1A2CYP2C19MAPTHPGD | |
| SCHEMBL6564104 | 0.78 | MAPT (0.47) | ALDH1A1CYP1A2CYP2C19MAPTHPGD | |
| SCHEMBL6693760 | 0.78 | MEN1 (0.40) | ALDH1A1CYP1A2CYP2C19TSHRMAPT | |
| SCHEMBL6426583 | 0.77 | MAPT (0.41) | ALDH1A1CYP1A2CYP2C19TSHRMAPT | |
| SCHEMBL30230387 | 0.76 | CA1 (0.41) | ALDH1A1TSHRHPGDSMN1; SMN2MEN1 | |
| SCHEMBL5101279 | 0.75 | MAPT (0.47) | ALDH1A1CYP1A2CYP2C19TSHRMAPT | |
| SCHEMBL28573033 | 0.75 | PDK1 (0.41) | ALDH1A1CYP1A2CYP2C19MAPTHPGD | |
| SCHEMBL6852251 | 0.72 | CNR1 (0.40) | ALDH1A1CYP1A2CYP2C19MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774086-B2 | HERBICIDES | BAYER CROPSCIENCE GMBH (DE) | 2004-08-10 | — | — | US | disclosed |
| US-20030191027-A1 | 3-Aminocarbonyl-substituted benzoylcyclohexanediones | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2003-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191027-A1 | 3-Aminocarbonyl-substituted benzoylcyclohexanediones | CYP1B1, CBR3, CBR1 | ALDH1A1 255/4885CYP1A2 7/4885CYP2C19 312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.