Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.32 |
| ▸ | HTR2C | P28335 | 3/20 | 0.32 |
| ▸ | HTR1B | P28222 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6690930 | 0.90 | TSHR (0.33) | TSHRHTR2AHTR2CHTR1BHTR2B | |
| SCHEMBL6693788 | 0.90 | MEN1 (0.35) | TSHRMAPTMEN1NPC1ALDH1A1 | |
| SCHEMBL6692273 | 0.83 | SNCA (0.40) | SMN1; SMN2MAPTRAB9AMEN1NPC1 | |
| SCHEMBL6691234 | 0.81 | HTR2A (0.32) | TSHRHTR2AHTR2CHTR1BHTR2B | |
| SCHEMBL6691232 | 0.80 | MEN1 (0.35) | TSHRMAPTMEN1NPC1ALDH1A1 | |
| SCHEMBL6690929 | 0.78 | LMNA (0.40) | TSHRMAPTALDH1A1GAAL3MBTL1 | |
| SCHEMBL6694327 | 0.75 | RAB9A (0.34) | TSHRHTR2AHTR2CHTR1BHTR2B | |
| SCHEMBL6697903 | 0.75 | CYP1A2 (0.38) | TSHRHTR2BMAPTMEN1ALDH1A1 | |
| SCHEMBL6697971 | 0.75 | CYP1A2 (0.38) | TSHRHTR2BMAPTMEN1ALDH1A1 | |
| SCHEMBL6697887 | 0.72 | HRH3 (0.33) | TSHRHTR2AHTR2CHTR1BHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869016-B1 | Pneumatic radial tires | BRIDGESTONE CORP (JP) | 2004-03-03 | — | — | EP | disclosed |
| US-6336486-B1 | Pneumatic radical tire having cap base tread | BRIDGESTONE CORPORATION (JP) | 2002-01-08 | — | — | US | disclosed |
| EP-0869016-A2 | Pneumatic radial tires | Bridgestone Corporation (JP) | 1998-10-07 | — | — | EP | disclosed |