SCHEMBL6693950

SCHEMBL6693950

COc1ccc(-c2c3ccccc3c(-c3ccc(C=O)cc3)c3ccccc23)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.66
CYP2A6 P11509 1/20 0.66
ACHE P22303 1/20 0.49
TRPA1 O75762 1/20 0.47
KMT2A Q03164 3/20 0.46
MEN1 O00255 2/20 0.46
USP2 O75604 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
MAOB P27338 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
RXFP1 Q9HBX9 1/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2C19 P33261 2/20 0.44
LMNA P02545 1/20 0.44
CYP2C9 P11712 1/20 0.44
PTGS2 P35354 1/20 0.43
HDAC4 P56524 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC8 Q9BY41 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29458789 0.85 ACHE (0.61) ALDH1A1ACHEMAOBCA1CA2
SCHEMBL4547729 0.85 ALDH1A1 (0.52) ALDH1A1CYP2A6DRD1
SCHEMBL1470672 0.85 ACHE (0.61) ALDH1A1ACHEMAOBCA1CA2
SCHEMBL6351 0.83 ALDH1A1 (0.86) ALDH1A1CYP2A6TRPA1CA1CA2
SCHEMBL19214399 0.83 ALDH1A1 (0.86) ALDH1A1CYP2A6TRPA1CA1CA2
SCHEMBL4309836 0.83 ACHE (0.54) ALDH1A1ACHETRPA1MAOBCA1
SCHEMBL13499831 0.82 ALDH1A1 (0.51) ALDH1A1CYP2A6TRPA1KMT2AMEN1
Biphenyl SCHEMBL10800283 0.82 ALDH1A1 (0.76) ALDH1A1CYP2A6TRPA1KMT2AMEN1
Anisaldehyde SCHEMBL20357563 0.81 ALDH1A1 (0.83) ALDH1A1CYP2A6TRPA1KMT2AMEN1
SCHEMBL21235656 0.81 ACHE (0.62) ALDH1A1ACHETDP1MAOBCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004092185-A1 LUMINESCENT LANTHANIDE (III) -CHELATED DENDRITIC COMPLEXES HAVING LIGHT-HARVESTING EFFECT AND THEIR SYNTHETIC METHODS KIM HWAN-KYU (KR) 2004-10-28 WO disclosed