Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 17/20 | 0.81 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | PTPRC | P08575 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22425029 | 0.76 | KMT2A (0.84) | MEN1KMT2A | |
| Propionic Acid SCHEMBL4155591 | 0.75 | BRD4 (0.50) | BRD4MEN1KMT2A | |
| SCHEMBL14722492 | 0.74 | BRD4 (0.61) | BRD4MEN1KMT2A | |
| SCHEMBL20769937 | 0.74 | MEN1 (0.50) | BRD4MEN1KMT2A | |
| SCHEMBL3246043 | 0.74 | BRD4 (0.48) | BRD4MEN1KMT2A | |
| SCHEMBL1459765 | 0.73 | AURKA (0.68) | — | |
| SCHEMBL16111911 | 0.73 | KDM4E (0.64) | BRD4MEN1KMT2A | |
| SCHEMBL28738670 | 0.72 | ATIC (0.49) | BRD4MEN1KMT2APTPRC | |
| SCHEMBL14594978 | 0.72 | BRD4 (0.68) | BRD4 | |
| SCHEMBL2763638 | 0.71 | ALDH1A1 (0.50) | BRD4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723733-B2 | POLYMERASE INHIBITOR | GUILFORD PHARMACEUTICALS, INC. | 2004-04-20 | — | — | US | disclosed |
| US-20020006927-A1 | Sulfonamide and carbamide derivatives of 6(5H)phenanthridinones and their uses | EISAI INC. | 2002-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020006927-A1 | Sulfonamide and carbamide derivatives of 6(5H)phenanthridinones and their uses | PARP1, PARP2, PARP6 | BRD4 77/4885MEN1 2882/4885KMT2A 260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.