Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 5/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | CPA1 | P15085 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30002045 | 0.76 | MME (0.53) | MMP2MMP9MAOBMMEACE | |
| SCHEMBL31441380 | 0.75 | MME (0.54) | MMP2MMP9MAOBMMEACE | |
| SCHEMBL11477747 | 0.74 | MEN1 (0.57) | MAOBMMEACECPA1ACE2 | |
| SCHEMBL6685553 | 0.74 | MAOB (0.56) | MAOBMMEACECPA1ACE2 | |
| SCHEMBL6685555 | 0.74 | MAOB (0.56) | MAOBMMEACECPA1ACE2 | |
| SCHEMBL6687176 | 0.73 | MAOB (0.65) | MAOB | |
| SCHEMBL6687173 | 0.73 | MAOB (0.65) | MAOB | |
| SCHEMBL6687904 | 0.72 | MAOB (0.56) | MAOBMMEACECPA1ACE2 | |
| SCHEMBL6687900 | 0.72 | MAOB (0.56) | MAOBMMEACECPA1ACE2 | |
| SCHEMBL30794012 | 0.71 | MAOB (0.61) | MAOBFFAR1PPARGPPARASLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087125-A1 | AMINO ACID DERIVATIVES AS INHIBITORS OF MAMMALIAN SODIUM CHANNELS | IONIX PHARMACEUTICALS LIMITED (GB) | 2004-10-14 | — | — | WO | disclosed |