SCHEMBL30002045

SCHEMBL30002045

CCN[C@@H](CC)C(=O)NCc1ccc(OCc2ccc(C(F)(F)F)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MME P08473 2/20 0.53
ACE P12821 2/20 0.53
CPA1 P15085 2/20 0.53
ACE2 Q9BYF1 2/20 0.53
MAOB P27338 5/20 0.53
FFAR1 O14842 3/20 0.49
PPARG P37231 1/20 0.49
PPARA Q07869 1/20 0.47
ADAMTS5 Q9UNA0 1/20 0.47
MMP2 P08253 1/20 0.46
MMP9 P14780 1/20 0.46
PLG P00747 1/20 0.45
PRSS1 P07477 1/20 0.45
PRSS2 P07478 1/20 0.45
PRSS3 P35030 1/20 0.45
SLC6A5 Q9Y345 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30001571 0.91 MME (0.52) MMEACECPA1ACE2MAOB
SCHEMBL31441380 0.90 MME (0.54) MMEACECPA1ACE2MAOB
Hydrochloric Acid SCHEMBL30002297 0.83 MAOB (0.54) MMEACECPA1ACE2MAOB
SCHEMBL30001612 0.81 MAOB (0.52) MMEACECPA1ACE2MAOB
SCHEMBL30794012 0.80 MAOB (0.61) MAOBFFAR1PPARGPPARAADAMTS5
SCHEMBL30001631 0.79 MME (0.48) MMEACECPA1ACE2MAOB
SCHEMBL30002243 0.78 MAOB (0.50) MMEACECPA1ACE2MAOB
SCHEMBL30604549 0.77 MAOB (0.52) MMEACECPA1ACE2MAOB
SCHEMBL11477747 0.76 MEN1 (0.57) MMEACECPA1ACE2MAOB
SCHEMBL6694097 0.76 MMP2 (0.52) MMEACECPA1ACE2MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250205195-A1 BENZYLOXY-BENZYLAMINYL AMINO ACID DERIVATIVE FOR ADJUSTING TSLP/TSLPR SIGNAL TRANSMISSION AMTIXBIO CO., LTD. (KR) 2025-06-26 US claimed
US-20250034085-A1 COMPOSITION AND METHODS FOR PREVENTING OR TREATING PHYTOPATHOGENIC FUNGAL INFECTION AMTIXBIO CO., LTD. (KR) 2025-01-30 US claimed
US-20250034083-A1 METHODS FOR PREPARING BENZYLOXYBENZYLAMINE AMINO ACID DERIVATIVES AMTIXBIO CO., LTD. (KR) 2025-01-30 US claimed
US-20250034084-A1 COMPOSITIONS AND METHODS FOR PREVENTING OR TREATING MYCOSIS AMTIXBIO CO., LTD. (KR) 2025-01-30 US claimed
EP-4349329-A1 BENZYLOXY-BENZYLAMINYL AMINO ACID DERIVATIVE FOR ADJUSTING TSLP/TSLPR SIGNAL TRANSMISSION Amtixbio Co., Ltd. (KR) 2024-04-10 EP claimed
CN-117677382-A Benzyloxy benzylamino amino acid derivatives that modulate TSLP/TSLPR signaling 阿米蒂比奥有限公司 2024-03-08 CN claimed
CN-110325509-B Functional derivative compounds of alanine and proline amino acids and pharmaceutical compositions containing the same 阿米蒂比奥有限公司 2024-02-02 CN claimed
WO-2022255801-A1 BENZYLOXY-BENZYLAMINYL AMINO ACID DERIVATIVE FOR ADJUSTING TSLP/TSLPR SIGNAL TRANSMISSION (주)앰틱스바이오 2022-12-08 WO claimed
US-20250205195-A1 BENZYLOXY-BENZYLAMINYL AMINO ACID DERIVATIVE FOR ADJUSTING TSLP/TSLPR SIGNAL TRANSMISSION AMTIXBIO CO., LTD. (KR) 2025-06-26 US disclosed
EP-4349329-A1 BENZYLOXY-BENZYLAMINYL AMINO ACID DERIVATIVE FOR ADJUSTING TSLP/TSLPR SIGNAL TRANSMISSION Amtixbio Co., Ltd. (KR) 2024-04-10 EP disclosed
CN-117677382-A Benzyloxy benzylamino amino acid derivatives that modulate TSLP/TSLPR signaling 阿米蒂比奥有限公司 2024-03-08 CN disclosed
CN-110325509-B Functional derivative compounds of alanine and proline amino acids and pharmaceutical compositions containing the same 阿米蒂比奥有限公司 2024-02-02 CN disclosed
CN-116836083-A Functional derivative compounds of alanine and proline amino acids and pharmaceutical compositions containing the same 阿米蒂比奥有限公司 2023-10-03 CN disclosed
WO-2022255801-A1 BENZYLOXY-BENZYLAMINYL AMINO ACID DERIVATIVE FOR ADJUSTING TSLP/TSLPR SIGNAL TRANSMISSION (주)앰틱스바이오 2022-12-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250034083-A1 METHODS FOR PREPARING BENZYLOXYBENZYLAMINE AMINO ACID DERIVATIVES BCAT2, BCAT1, DAO MME 365/4885ACE 411/4885CPA1 265/4885
US-20250034084-A1 COMPOSITIONS AND METHODS FOR PREVENTING OR TREATING MYCOSIS ERG28, BCAT2, AADAT MME 532/4885ACE 238/4885CPA1 117/4885
US-20250034085-A1 COMPOSITION AND METHODS FOR PREVENTING OR TREATING PHYTOPATHOGENIC FUNGAL INFECTION PEPD, PREP, ANPEP MME 821/4885ACE 178/4885CPA1 58/4885
US-20250205195-A1 BENZYLOXY-BENZYLAMINYL AMINO ACID DERIVATIVE FOR ADJUSTING TSLP/TSLPR SIGNAL TRANSMISSION TSLP, IL2RA, TRPC7 MME 662/4885ACE 2125/4885CPA1 1646/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.