Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.47 |
| ▸ | FNTA | P49354 | 6/20 | 0.39 |
| ▸ | FNTB | P49356 | 6/20 | 0.39 |
| ▸ | TGM2 | P21980 | 3/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | PGGT1B | P53609 | 4/20 | 0.35 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6018231 | 0.89 | FOLH1 (0.41) | FOLH1FNTAFNTBTGM2SLC40A1 | |
| SCHEMBL27566358 | 0.86 | TGM2 (0.37) | FOLH1FNTAFNTBTGM2NCOA3 | |
| SCHEMBL6018172 | 0.85 | FOLH1 (0.50) | FOLH1FNTAFNTBTGM2NCOA3 | |
| SCHEMBL6683363 | 0.83 | FOLH1 (0.41) | FOLH1FNTAFNTBTGM2SLC40A1 | |
| SCHEMBL6682711 | 0.83 | CXCR4 (0.40) | FOLH1FNTAFNTBTGM2CASR | |
| SCHEMBL6018129 | 0.83 | CXCR4 (0.51) | FOLH1FNTAFNTBTGM2PGGT1B | |
| SCHEMBL6018396 | 0.82 | TGM2 (0.37) | FOLH1TGM2 | |
| SCHEMBL6690468 | 0.82 | CXCR4 (0.40) | FOLH1FNTAFNTBTGM2PGGT1B | |
| SCHEMBL6690684 | 0.82 | CXCR4 (0.40) | FOLH1FNTAFNTBTGM2PGGT1B | |
| SCHEMBL6654738 | 0.80 | CXCR4 (0.42) | FOLH1TGM2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389460-A1 | CXCR4-ANTAGONISTIC DRUGS COMPRISING NITROGEN-CONTAINING COMPOUND | Kureha Chemical Industry Co., Ltd. (JP) | 2004-02-18 | — | — | EP | disclosed |