Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.59 |
| ▸ | PI4KA | P42356 | 2/20 | 0.59 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.59 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.59 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.59 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | ADCY5 | O95622 | 5/20 | 0.55 |
| ▸ | AHCY | P23526 | 2/20 | 0.55 |
| ▸ | SRC | P12931 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL985545 | 0.86 | ADCY5 (0.63) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL29728010 | 0.86 | ADORA2A (0.60) | EGFRADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL1565498 | 0.86 | ADORA2A (0.60) | EGFRADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL9435719 | 0.85 | PI4KA (0.62) | EGFRADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL27713663 | 0.84 | EGFR (0.64) | EGFRADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL6045668 | 0.83 | ADCY5 (0.72) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL1673251 | 0.82 | EGFR (0.70) | EGFRADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL17165347 | 0.82 | EGFR (0.66) | EGFRADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL8839812 | 0.80 | ADORA2A (0.56) | EGFRADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL24709730 | 0.78 | EGFR (0.65) | EGFRADORA2AADORA1PI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159536-A1 | PYRROLOPYRIMIDINE AMINES AS COMPLEMENT INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2023-05-25 | — | — | US | disclosed |
| US-6825348-B2 | Antiviral compounds | ACADEMIA SINICA (TW) | 2004-11-30 | — | — | US | disclosed |
| US-20040002475-A1 | Dna genome | ACADEMIA SINICA (TW) | 2004-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159536-A1 | PYRROLOPYRIMIDINE AMINES AS COMPLEMENT INHIBITORS | C5, C9, C1QBP | EGFR 2721/4885ADORA2A 1283/4885ADORA1 897/4885 |
| US-20040002475-A1 | Dna genome | DNA2, OGG1, UNG | EGFR 2221/4885ADORA2A 122/4885ADORA1 77/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.