Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.67 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.67 |
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CCND1 | P24385 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | JUN | P05412 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | NAT1 | P18440 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicyladehyde SCHEMBL3379353 | 0.92 | TRIM24 (0.78) | TRIM24TRIM33ERN1CDK4CCND1 | |
| Ortho-Phthalaldehyde SCHEMBL7621085 | 0.86 | LMNA (0.59) | TRIM24TRIM33ERN1LMNAMEN1 | |
| Salicyladehyde SCHEMBL28887959 | 0.84 | TRIM24 (0.95) | TRIM24TRIM33ERN1CDK4CCND1 | |
| Salicyladehyde SCHEMBL6917405 | 0.84 | TRIM24 (0.95) | TRIM24TRIM33ERN1CDK4CCND1 | |
| Salicyladehyde SCHEMBL27901835 | 0.82 | TRIM24 (0.62) | TRIM24TRIM33ERN1CDK4CCND1 | |
| Salicyladehyde SCHEMBL29386538 | 0.82 | — | — | |
| Salicyladehyde SCHEMBL15395 | 0.82 | — | — | |
| Salicyladehyde SCHEMBL901265 | 0.82 | TRIM24 (1.00) | TRIM24TRIM33ERN1CDK4CCND1 | |
| Salicyladehyde SCHEMBL23389487 | 0.80 | TRIM24 (0.95) | TRIM24TRIM33ERN1CDK4CCND1 | |
| Salicyladehyde SCHEMBL5121332 | 0.80 | TRIM24 (0.95) | TRIM24TRIM33ERN1CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635004-B1 | 4-DIPHENYLMETHYL PIPERIDINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | MERRELL PHARMA INC (US) | 2002-07-17 | — | — | EP | claimed |
| US-5652370-A | Process for piperidine derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1997-07-29 | — | — | US | claimed |
| US-5650516-A | Process for piperidine derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1997-07-22 | — | — | US | claimed |
| EP-0635004-A1 | 4-DIPHENYLMETHYL PIPERIDINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | MERRELL PHARMACEUTICALS INC. (US) | 1995-01-25 | — | — | EP | claimed |
| WO-1993021156-A1 | 4-DIPHENYLMETHYL PIPERIDINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-10-28 | — | — | WO | claimed |
| JP-2004285072-A | NEW PIPERIDINE DERIVATIVES | MERRELL PHARMACEUTICALS INC | 2004-10-14 | — | — | JP | disclosed |