Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 8/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6350509 | 0.83 | PPARA (0.41) | TBXAS1PPARANPC1RAB9A | |
| SCHEMBL6347269 | 0.82 | PPARA (0.42) | ALDH1A1TBXAS1PPARANPC1RAB9A | |
| SCHEMBL9321972 | 0.74 | PPARA (0.47) | TBXAS1PPARA | |
| SCHEMBL11762158 | 0.72 | CES1 (0.44) | ALDH1A1HPGDPPARANPC1RAB9A | |
| SCHEMBL11664524 | 0.69 | CES1 (0.51) | PPARA | |
| SCHEMBL11782068 | 0.69 | CES1 (0.51) | PPARA | |
| SCHEMBL6346750 | 0.69 | CES1 (0.41) | NPC1RAB9A | |
| SCHEMBL6509686 | 0.68 | CES1 (0.33) | ALDH1A1HPGD | |
| SCHEMBL3282682 | 0.68 | L3MBTL1 (0.47) | ALDH1A1TBXAS1PPARA | |
| SCHEMBL1728463 | 0.67 | CES1 (0.52) | ALDH1A1HPGDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004532799-A | — | — | 2004-10-28 | — | — | JP | claimed |
| EP-1363879-A2 | SULFIDE AND DISULFIDE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | Esperion Therapeutics Inc. (US) | 2003-11-26 | — | — | EP | claimed |
| WO-2002030884-A2 | SULFIDE AND DISULFIDE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2002-04-18 | — | — | WO | claimed |