Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.70 |
| ▸ | TSHR | P16473 | 5/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.70 |
| ▸ | LMNA | P02545 | 4/20 | 0.70 |
| ▸ | POLB | P06746 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.70 |
| ▸ | XBP1 | P17861 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 8/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6691113 | 0.93 | ALDH1A1 (0.74) | ALDH1A1TSHRKMT2ALMNAPOLB | |
| SCHEMBL14366839 | 0.91 | ALDH1A1 (0.76) | ALDH1A1TSHRKMT2ALMNAPOLB | |
| SCHEMBL6690424 | 0.90 | ALDH1A1 (0.79) | ALDH1A1TSHRKMT2ALMNAPOLB | |
| SCHEMBL6688827 | 0.85 | TSHR (0.61) | ALDH1A1TSHRKMT2ALMNAPOLB | |
| SCHEMBL6689882 | 0.85 | ALDH1A1 (0.60) | ALDH1A1TSHRKMT2ALMNAPOLB | |
| SCHEMBL6692102 | 0.84 | ALDH1A1 (0.77) | ALDH1A1TSHRKMT2ALMNAPOLB | |
| SCHEMBL14366818 | 0.84 | MAPT (0.71) | ALDH1A1TSHRKMT2ALMNAPOLB | |
| SCHEMBL6688843 | 0.83 | ALDH1A1 (0.82) | ALDH1A1TSHRKMT2ALMNAPOLB | |
| SCHEMBL5606330 | 0.82 | ALDH1A1 (1.00) | ALDH1A1TSHRKMT2ALMNAPOLB | |
| SCHEMBL14366838 | 0.82 | ALDH1A1 (0.83) | ALDH1A1TSHRKMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004096808-A1 | TRIAZINE COMPOUNDS AND THEIR USE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-11-11 | — | — | WO | disclosed |