Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 3/20 | 0.72 |
| ▸ | EGFR | P00533 | 3/20 | 0.72 |
| ▸ | IGF1R | P08069 | 1/20 | 0.72 |
| ▸ | MAP1LC3B | Q9GZQ8 | 3/20 | 0.67 |
| ▸ | PLK4 | O00444 | 4/20 | 0.62 |
| ▸ | PLK1 | P53350 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | CTRC | Q99895 | 1/20 | 0.57 |
| ▸ | RAF1 | P04049 | 4/20 | 0.55 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.55 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.55 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.55 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.55 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.55 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.55 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.55 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.55 |
| ▸ | ARAF | P10398 | 1/20 | 0.55 |
| ▸ | PIM1 | P11309 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6688476 | 0.90 | ERBB2 (0.72) | ERBB2EGFRIGF1RMAP1LC3BPLK4 | |
| SCHEMBL7319107 | 0.86 | ERBB2 (0.73) | ERBB2EGFRIGF1RMAP1LC3BPLK4 | |
| SCHEMBL7319104 | 0.86 | ERBB2 (0.73) | ERBB2EGFRIGF1RMAP1LC3BPLK4 | |
| SCHEMBL5468784 | 0.85 | LRRK2 (0.72) | ERBB2EGFRIGF1RCTRCLRRK2 | |
| SCHEMBL5468785 | 0.85 | LRRK2 (0.72) | ERBB2EGFRIGF1RCTRCLRRK2 | |
| SCHEMBL1394846 | 0.84 | MAP1LC3B (0.71) | EGFRMAP1LC3BPLK4PLK1MEN1 | |
| SCHEMBL1394844 | 0.84 | MAP1LC3B (0.71) | EGFRMAP1LC3BPLK4PLK1MEN1 | |
| SCHEMBL6687017 | 0.84 | LRRK2 (0.73) | EGFRMAP1LC3BPLK4PLK1MEN1 | |
| SCHEMBL5472251 | 0.84 | ERBB2 (1.00) | ERBB2EGFRIGF1RPLK4PLK1 | |
| SCHEMBL5472252 | 0.84 | ERBB2 (1.00) | ERBB2EGFRIGF1RPLK4PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004069998-A2 | OXINDOLE DERIVATIVES AS ANTIMICROBIAL AGENTS | ARROW THERAPEUTICS LIMITED (GB) | 2004-08-19 | — | — | WO | disclosed |