Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6596322 | 0.81 | ADAM17 (0.75) | ADAM17MMP13 | |
| SCHEMBL6696849 | 0.80 | ADAM17 (0.89) | ADAM17MMP13 | |
| SCHEMBL6595886 | 0.77 | ADAM17 (0.65) | ADAM17MMP13 | |
| SCHEMBL6597646 | 0.76 | ADAM17 (1.00) | ADAM17MMP13 | |
| SCHEMBL6596356 | 0.76 | ADAM17 (0.91) | ADAM17MMP13 | |
| SCHEMBL6596079 | 0.76 | ADAM17 (0.63) | ADAM17 | |
| SCHEMBL6596595 | 0.76 | ADAM17 (1.00) | ADAM17MMP13 | |
| SCHEMBL6595754 | 0.76 | ADAM17 (1.00) | ADAM17MMP13 | |
| SCHEMBL6596627 | 0.76 | ADAM17 (0.88) | ADAM17MMP13 | |
| SCHEMBL6594734 | 0.76 | ADAM17 (0.84) | ADAM17MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040072802-A1 | Beta-amino acid derivatives as inhibitors of matrix metalloproteases and TNF-alpha | DUAN JINGWU (US) | 2004-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072802-A1 | Beta-amino acid derivatives as inhibitors of matrix metalloproteases and TNF-alpha | TNF, XPNPEP1, MMP2 | ADAM17 29/4885MMP13 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.