Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6694096 | 0.98 | ALDH1A1 (0.40) | ALDH1A1LPAR1LPAR3MEN1KMT2A | |
| SCHEMBL6697213 | 0.95 | LMNA (0.42) | ALDH1A1LPAR1LPAR3MEN1KMT2A | |
| SCHEMBL6697793 | 0.91 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL32688856 | 0.89 | ALDH1A1 (0.42) | ALDH1A1LPAR1LPAR3EPHX2ENPP2 | |
| SCHEMBL32688733 | 0.85 | ALDH1A1 (0.44) | ALDH1A1LPAR1LPAR3MEN1KMT2A | |
| SCHEMBL6697591 | 0.84 | MEN1 (0.45) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL10358420 | 0.81 | MEN1 (0.41) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9810566 | 0.80 | MEN1 (0.42) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL31716524 | 0.79 | MEN1 (0.42) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL13277673 | 0.79 | MEN1 (0.42) | ALDH1A1MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040210081-A1 | Carboxylic esters based on 2-hydroxymethylnorbornane | CELANESE CHEMICALS EUROPE GMBH (DE) | 2004-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040210081-A1 | Carboxylic esters based on 2-hydroxymethylnorbornane | TAF1, HSD17B10, SULT1E1 | ALDH1A1 182/4885LPAR1 3563/4885LPAR3 4356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.