SCHEMBL669562

SCHEMBL669562

C[C@H](N)C(=O)Oc1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.76

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ELANE P08246 11/20 0.76
STS P08842 1/20 0.50
MEN1 O00255 1/20 0.49
NPC1 O15118 1/20 0.49
KMT2A Q03164 1/20 0.49
POLB P06746 1/20 0.48
PARP10 Q53GL7 1/20 0.47
ALDH1A1 P00352 1/20 0.47
GAA P10253 1/20 0.46
SRD5A2 P31213 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10483706 0.86 ELANE (1.00) ELANESTSMEN1NPC1KMT2A
SCHEMBL133568 0.86 ELANE (0.53) ELANEMEN1NPC1KMT2AALDH1A1
SCHEMBL9939655 0.86 ELANE (0.53) ELANEMEN1NPC1KMT2AALDH1A1
SCHEMBL285949 0.86 ELANE (0.53) ELANEMEN1NPC1KMT2AALDH1A1
SCHEMBL364405 0.84 KMT2A (0.56) ELANEKMT2APARP10ALDH1A1SRD5A2
Hydrochloric Acid SCHEMBL19834657 0.84 ELANE (0.51) ELANEMEN1NPC1KMT2AALDH1A1
Hydrochloric Acid SCHEMBL10445713 0.84 ELANE (0.51) ELANEMEN1NPC1KMT2AALDH1A1
Ammonia Solution, Strong SCHEMBL9613925 0.84 ELANE (0.51) ELANEMEN1NPC1KMT2AALDH1A1
Ammonia Solution, Strong SCHEMBL2037585 0.84 ELANE (0.51) ELANEMEN1NPC1KMT2AALDH1A1
SCHEMBL28281300 0.84 ELANE (0.51) ELANEMEN1NPC1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3908306-A1 PHOSPHATASE BINDING COMPOUNDS AND METHODS OF USING SAME Yale University (US) 2021-11-17 EP claimed
CN-113481228-A Microorganism unnatural amino acid introduction system and construction method 中国药科大学 2021-10-08 CN claimed
WO-2020146470-A1 Phosphatase Binding Compounds and Methods of Using Same YALE UNIVERSITY (US) 2020-07-16 WO claimed
US-12351857-B2 Activity based probes UNIVERSITY OF DUNDEE (GB) 2025-07-08 US disclosed
US-20220267825-A1 ACTIVITY BASED PROBES UNIVERSITY OF DUNDEE (GB) 2022-08-25 US disclosed
EP-4021926-A1 ACTIVITY BASED PROBES University of Dundee (GB) 2022-07-06 EP disclosed
EP-3923974-A1 IL-2 CONJUGATES AND METHODS OF USE THEREOF Synthorx, Inc. (US) 2021-12-22 EP disclosed
EP-3908306-A1 PHOSPHATASE BINDING COMPOUNDS AND METHODS OF USING SAME Yale University (US) 2021-11-17 EP disclosed
CN-113481228-A Microorganism unnatural amino acid introduction system and construction method 中国药科大学 2021-10-08 CN disclosed
EP-3830580-A1 BIOSENSORS FOR DETECTING ARRESTIN SIGNALING Montana Molecular LLC (US) 2021-06-09 EP disclosed
WO-2021038034-A1 ACTIVITY BASED PROBES UNIVERSITY OF DUNDEE (GB) 2021-03-04 WO disclosed
EP-2046814-A2 MINIMIZED SMALL PEPTIDES WITH HIGH AFFINITY FOR FACTOR VIII AND FACTOR VIII-LIKE PROTEINS Technische Universität München (DE) 2009-04-15 EP disclosed
WO-2008121836-A1 COMPOUNDS AND METHODS FOR ENHANCING MHC CLASS II THERAPIES BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2008-10-09 WO disclosed
WO-2008003707-A2 MINIMIZED SMALL PEPTIDES WITH HIGH AFFINITY FOR FACTOR VIII AND FACTOR VIII-LIKE PROTEINS Technische Universität München (DE) 2008-01-10 WO disclosed
CN-1688600-A Template-fixed peptidomimetics with antibacterial activity POLYPHOR LTD (CH) 2005-10-26 CN disclosed
CN-1582296-A Template-fixed peptidomimetics as serine protease inhibitors POLYPHOR LTD (CH) 2005-02-16 CN disclosed
CN-1163261-C Method of treating skin pigmentation ���Ǿ� 2004-08-25 CN disclosed
US-20030114362-A1 Penta-or tetrapeptide binding to somatostatin receptors and the use of the same NOVASPIN BIOTECH GMBH (DE) 2003-06-19 US disclosed
WO-2002100885-A2 A PENTA- OR TETRAPEPTIDE BINDING TO SOMATOSTATIN RECEPTORS AND THE USE OF THE SAME NOVASPIN BIOTECH GMBH (DE) 2002-12-19 WO disclosed
CN-1283507-A Method of treating skin pigmentation JOHNSON & JOHNSON CONSUMER (US) 2001-02-14 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030114362-A1 Penta-or tetrapeptide binding to somatostatin receptors and the use of the same SSTR5, SSTR3, SCTR ELANE 302/4885STS 1097/4885MEN1 629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.