Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.69 |
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | NSD2 | O96028 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | HKDC1 | Q2TB90 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | ATIC | P31939 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1806130 | 0.83 | MCL1 (0.79) | THRBKDM4EMAPTKMT2AMCL1 | |
| SCHEMBL317180 | 0.83 | THRB (1.00) | THRBKDM4EMAPTKMT2AMCL1 | |
| Methylamine SCHEMBL9769432 | 0.82 | THRB (0.89) | THRBKDM4EMAPTKMT2AMCL1 | |
| SCHEMBL17779197 | 0.82 | PKM (0.55) | THRBKDM4EMAPTKMT2AMCL1 | |
| SCHEMBL29904678 | 0.82 | MAPT (1.00) | THRBKDM4EMAPTKMT2AMCL1 | |
| SCHEMBL10902143 | 0.82 | MAPT (1.00) | THRBKDM4EMAPTKMT2AMCL1 | |
| SCHEMBL10426719 | 0.82 | THRB (0.69) | THRBKDM4EMAPTKMT2AMCL1 | |
| SCHEMBL10418680 | 0.81 | THRB (0.53) | THRBKDM4EMAPTKMT2AMCL1 | |
| SCHEMBL14432590 | 0.80 | KDM4E (0.73) | THRBKDM4EMAPTKMT2AMCL1 | |
| SCHEMBL19423432 | 0.80 | HSD17B10 (0.47) | THRBKDM4EMAPTKMT2AMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004109398-A1 | PHOTOGRAPHIC ELEMENT CONTAINING IMPROVED COUPLER MOIETY | EASTMAN KODAK COMPANY (US) | 2004-12-16 | — | — | WO | disclosed |
| US-6780573-B1 | ADEQUATE DIFFUSION RESISTANCE WITHOUT BALLAST; MINIMIZED SPEED LOSS; GREATER INTERIMAGE; EFFICIENT REMOVAL | EASTMAN KODAK COMPANY | 2004-08-24 | — | — | US | disclosed |
| EP-0576088-B1 | Photographic material and process comprising a coupler capable of forming a wash-out dye | EASTMAN KODAK CO (US) | 1999-08-11 | — | — | EP | disclosed |
| US-5288593-A | Photographic material and process comprising a coupler capable of forming a wash-out dye (Q/Q) | EASTMAN KODAK COMPANY (US) | 1994-02-22 | — | — | US | disclosed |
| US-5279929-A | Coupler forms a compound that washes out during development | EASTMAN KODAK COMPANY (US) | 1994-01-18 | — | — | US | disclosed |
| EP-0577182-A1 | Photographic material and process comprising a coupler capable of forming a wash-out dye (Q/Q) | EASTMAN KODAK COMPANY (US) | 1994-01-05 | — | — | EP | disclosed |
| EP-0576087-A1 | Photographic material and process comprising a coupler capable of forming a wash-out dye (Q/C) | EASTMAN KODAK COMPANY (US) | 1993-12-29 | — | — | EP | disclosed |
| EP-0576089-A2 | Photographic material and process comprising a coupler capable of forming a wash-out dye | EASTMAN KODAK COMPANY (US) | 1993-12-29 | — | — | EP | disclosed |
| EP-0576052-A1 | Method of forming a photographic coupler capable of forming a wash-out dye | EASTMAN KODAK COMPANY (US) | 1993-12-29 | — | — | EP | disclosed |
| EP-0576088-A1 | Photographic material and process comprising a coupler capable of forming a wash-out dye (C/C) | EASTMAN KODAK COMPANY (US) | 1993-12-29 | — | — | EP | disclosed |
| US-5264582-A | Reaction of hydroxyaryl aldehyde or ketone with a halomethyl compound to form ether compound and reducing the product then halogenation and reaction with photographic coupler | EASTMAN KODAK COMPANY (US) | 1993-11-23 | — | — | US | disclosed |
| US-5264583-A | Photographic coupler and method of making the same | EASTMAN KODAK COMPANY (US) | 1993-11-23 | — | — | US | disclosed |