Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 2/20 | 0.46 |
| ▸ | ESRRA | P11474 | 5/20 | 0.45 |
| ▸ | RET | P07949 | 2/20 | 0.44 |
| ▸ | PLK4 | O00444 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6696048 | 1.00 | ERBB2 (0.46) | ERBB2ESRRARETPLK4MEN1 | |
| SCHEMBL5472632 | 0.80 | MDM2 (0.52) | RETMEN1KMT2ACYP3A4NTRK1 | |
| SCHEMBL14448950 | 0.80 | MDM2 (0.52) | RETMEN1KMT2ACYP3A4NTRK1 | |
| SCHEMBL5472626 | 0.80 | MDM2 (0.52) | RETMEN1KMT2ACYP3A4NTRK1 | |
| SCHEMBL6405476 | 0.78 | ERBB2 (0.71) | ERBB2PLK4DHFREGFRCYP3A4 | |
| SCHEMBL6405474 | 0.78 | ERBB2 (0.71) | ERBB2PLK4DHFREGFRCYP3A4 | |
| SCHEMBL6689535 | 0.77 | ESRRA (0.53) | ERBB2ESRRARETPLK4DHFR | |
| SCHEMBL6689531 | 0.77 | ESRRA (0.53) | ERBB2ESRRARETPLK4DHFR | |
| SCHEMBL6692556 | 0.74 | EGFR (0.43) | ERBB2PLK4MEN1KMT2ADHFR | |
| SCHEMBL6692550 | 0.74 | EGFR (0.43) | ERBB2PLK4MEN1KMT2ADHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004069998-A2 | OXINDOLE DERIVATIVES AS ANTIMICROBIAL AGENTS | ARROW THERAPEUTICS LIMITED (GB) | 2004-08-19 | — | — | WO | disclosed |