Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PPARD | Q03181 | 4/20 | 0.45 |
| ▸ | DHODH | Q02127 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12374641 | 0.79 | PTGS1 (1.00) | PTGS1KDM4EALDH1A1TP53MEN1 | |
| SCHEMBL22570862 | 0.79 | PTGS1 (0.73) | PTGS1KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL5777104 | 0.79 | PTGS1 (0.65) | PTGS1KDM4EMAPTALDH1A1TP53 | |
| SCHEMBL17845096 | 0.77 | PTGS1 (0.60) | PTGS1KDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL12374640 | 0.74 | PTGS1 (1.00) | PTGS1KDM4EMAPTALDH1A1TP53 | |
| SCHEMBL899374 | 0.73 | GPBAR1 (0.53) | MAPTALDH1A1TP53L3MBTL1LMNA | |
| SCHEMBL16502243 | 0.71 | PTGS1 (0.73) | PTGS1KDM4EMAPTALDH1A1TP53 | |
| SCHEMBL16698055 | 0.71 | HSD17B10 (0.53) | PTGS1MAPTALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL6695232 | 0.70 | MAPT (0.57) | KDM4EMAPTALDH1A1TP53LMNA | |
| SCHEMBL13615438 | 0.70 | HTT (0.54) | PTGS1ALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040077675-A1 | Compounds and methods for inhibiting MRP1 | BONJOUKLIAN ROSANNE (US) | 2004-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077675-A1 | Compounds and methods for inhibiting MRP1 | ABCC1, ABCB1, ABCB11 | PTGS1 606/4885KDM4E 4499/4885MAPT 4342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.