Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 2/20 | 0.59 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.59 |
| ▸ | VCP | P55072 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | JUN | P05412 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL691995 | 0.85 | — | — | |
| SCHEMBL691994 | 0.85 | — | — | |
| SCHEMBL8542749 | 0.82 | CYP11B2 (0.61) | CYP11B2CYP11B1VCPRAB9ANPC1 | |
| SCHEMBL30444997 | 0.82 | CYP11B2 (0.61) | CYP11B2CYP11B1VCPRAB9ANPC1 | |
| SCHEMBL8542746 | 0.82 | CYP11B2 (0.61) | CYP11B2CYP11B1VCPRAB9ANPC1 | |
| SCHEMBL29691623 | 0.80 | CYP11B1 (0.86) | CYP11B2CYP11B1VCPRAB9ANPC1 | |
| SCHEMBL29691639 | 0.80 | CYP11B1 (0.86) | CYP11B2CYP11B1VCPRAB9ANPC1 | |
| SCHEMBL22511784 | 0.80 | CYP11B1 (0.59) | CYP11B2CYP11B1VCPRAB9ANPC1 | |
| SCHEMBL6249186 | 0.78 | CYP11B1 (0.57) | CYP11B2CYP11B1VCPRAB9ANPC1 | |
| SCHEMBL27626846 | 0.78 | CYP11B1 (0.57) | CYP11B2CYP11B1VCPRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825172-B2 | BACTERICIDES; AGAINST GRAMNEGATIVE, GRAMPOSITIVE BACTERIA | JANSSEN PHARMACEUTICA, NV (BE) | 2004-11-30 | — | — | US | disclosed |
| US-20040018994-A1 | 3-Descladinosyl-6-O-carbamoyl and 6-O-carbonoyl macrolide antibacterial agents | JANSSEN PHARMACEUTICA N.V. (BE) | 2004-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040018994-A1 | 3-Descladinosyl-6-O-carbamoyl and 6-O-carbonoyl macrolide antibacterial agents | CHCHD6, MRPL21, MRPS18B | CYP11B2 2734/4885CYP11B1 2206/4885VCP 1670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.