MRPS18B — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to MRPS18B by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Effect of WHO-yaws Elimination Strategy in Lihir Island, Papua New Guinea	PHASE3	COMPLETED
Antiviral Activity and Safety of 3 Different Doses of Mifepristone in Hepatitis C Infected Patients	PHASE2	COMPLETED
Mobilization of Stem Cells With G-CSF for Collection From Patients With Diamond-Blackfan Anemia	PHASE2	COMPLETED
ISIS 183750 With Irinotecan for Advanced Solid Tumors or Colorectal Cancer	PHASE1/PHASE2	COMPLETED
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma	PHASE1	COMPLETED
Assessing the Safety, Tolerability, and Efficacy of APR-2020 in Pediatric and Adolescent Subjects With RPS19 Deficient Diamond-Blackfan Anemia	PHASE1	RECRUITING
Role of Sorcin and Annexin A3 in Breast Cancer Patients	nan	UNKNOWN
Micro Ribosomal Nucleic Acid 155 in Non Hodgkin Lymphoma	nan	COMPLETED
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy	nan	UNKNOWN
Effect of Branched Chain Amino Acids on Muscle	nan	COMPLETED
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases	nan	UNKNOWN
Aberrant Splicings Due to Microsatellite Instability in Colorectal Cancer : Physiopathological and Clinical Impact	nan	UNKNOWN
RibOSE - Glucose and Resistance Exercise Training	nan	COMPLETED
Role of RPL8 Protein Alterations in High-grade Serous Ovarian Carcinoma	nan	RECRUITING
Protein Synthesis in the Brain of Patients With Fragile X Syndrome	nan	COMPLETED
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus	nan	COMPLETED
Mobilization of CD34+ Peripheral Blood Stem Cells in Patients With Diamond Blackfan Anemia Syndrome (DBAS)	nan	RECRUITING
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia	nan	NOT_YET_RECRUITING
Advancing Neurogenetic Diagnoses Through Long-Read Sequencing	nan	NOT_YET_RECRUITING
Impact of Mutations in Aminoacyl tRNA Synthetases on Protein Translation and Cellular Stress	nan	WITHDRAWN
Pharmacogenomics of Interferon and Ribavirin Treatment in Patients With Chronic Hepatitis C Virus Infection	nan	UNKNOWN
Mapping Novel Disease Genes for Dilated Cardiomyopathy	nan	COMPLETED
Autosomal Dominant Retinitis Pigmentosa: Prevalence of Known Genes Identification of New Loci / Genes	nan	COMPLETED
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic	nan	COMPLETED
Long Term Prediction of MASH-related HCC Risk by Proteomics	nan	NOT_YET_RECRUITING
Investigations Into ISCU Myopathy or Iron Sulfur Scaffold U Protein Myopathy	nan	COMPLETED
Identification of New FTLD Genes	nan	UNKNOWN
Molecular Genetic Epidemiology of Endocardial Cushion Defects - SCOR in Pediatric Cardiovascular Disease	nan	COMPLETED
Genomewide Search for Loci Underlying Metabolic Syndrome	nan	COMPLETED
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a MRPS18B binder may also engage these)

Protein	Name	Similarity
Q1XHY1	—	1.000	Q1XHY1 →
Q5TM62	—	1.000	Q5TM62 →
Q99N84	—	1.000	Q99N84 →
P82918	—	1.000	P82918 →
Q767K8	—	1.000	Q767K8 →
A1A4J7	—	0.974	A1A4J7 →
Q9DCI9	—	0.973	Q9DCI9 →
Q0MQJ3	—	0.973	Q0MQJ3 →
Q9DCJ7	—	0.972	Q9DCJ7 →
Q8VDP4	—	0.972	Q8VDP4 →
Q99N85	—	0.972	Q99N85 →
Q8HXG5	—	0.971	Q8HXG5 →
O88480	—	0.971	O88480 →
Q7Z7J5	—	0.971	Q7Z7J5 →
Q2TBI6	—	0.971	Q2TBI6 →
Q6EE22	—	0.971	Q6EE22 →
Q5R8S0	—	0.970	Q5R8S0 →
Q3T1H2	—	0.970	Q3T1H2 →
Q0MQJ4	—	0.970	Q0MQJ4 →
P82913	—	0.970	P82913 →
Q9Z136	—	0.970	Q9Z136 →
P0C279	—	0.970	P0C279 →
Q9D479	—	0.970	Q9D479 →
Q0MQJ5	—	0.970	Q0MQJ5 →
D3ZND0	—	0.970	D3ZND0 →
Q8CCG4	—	0.970	Q8CCG4 →
NDUFB11	NADH dehydrogenase [ubiquinone] 1 beta subcom	0.970	landscape →
Q5R8M4	—	0.970	Q5R8M4 →
P70166	—	0.970	P70166 →
O14525	—	0.970	O14525 →