Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 6/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6367295 | 0.88 | CHRM2 (0.44) | PREPCHRM2CHRM1CHRM3HPGD | |
| SCHEMBL241567 | 0.85 | CHRM2 (0.44) | PREPCHRM2CHRM1CHRM3HSD17B10 | |
| SCHEMBL241566 | 0.85 | CHRM2 (0.44) | PREPCHRM2CHRM1CHRM3HSD17B10 | |
| SCHEMBL12684291 | 0.85 | CHRM2 (0.44) | PREPCHRM2CHRM1CHRM3HSD17B10 | |
| SCHEMBL6167884 | 0.82 | DPP4 (0.41) | PREPCHRM2CHRM1CHRM3 | |
| SCHEMBL9183787 | 0.82 | PREP (0.53) | PREPHSD17B10HPGD | |
| SCHEMBL9321893 | 0.82 | PREP (0.56) | PREPHPGD | |
| SCHEMBL9321884 | 0.82 | PREP (0.56) | PREPHPGD | |
| SCHEMBL8549192 | 0.82 | PREP (0.56) | PREPHPGD | |
| SCHEMBL9323319 | 0.81 | PREP (0.55) | PREPHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071454-A2 | SUBSTITUTED AZETIDINE COMPOUNDS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | GUILFORD PHARMACEUTICALS INC. (US) | 2004-08-26 | — | — | WO | disclosed |