Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14497383 | 0.79 | NOTUM (0.46) | MAPTALDH1A1SLC18A3MEN1KMT2A | |
| SCHEMBL2899067 | 0.79 | NOTUM (0.46) | MAPTALDH1A1SLC18A3MEN1KMT2A | |
| SCHEMBL6696588 | 0.78 | GBA1 (0.57) | MAPTPOLBCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL3337833 | 0.78 | GBA1 (0.57) | MAPTPOLBCYP2C9CYP2C19ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6698454 | 0.77 | GFER (0.38) | MAPTPOLBALDH1A1GBA1SLC18A3 | |
| SCHEMBL3552397 | 0.77 | MAPT (0.56) | MAPTPOLBCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL3552399 | 0.77 | MAPT (0.56) | MAPTPOLBCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL9660476 | 0.77 | MAPT (0.56) | MAPTPOLBCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL38659875 | 0.75 | MAPT (0.51) | MAPTPOLBCYP2C9CYP2C19ALDH1A1 | |
| Carbamic Acid SCHEMBL14715641 | 0.75 | MAPT (0.47) | MAPTPOLBCYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040083559-A1 | Dyeing composition based on 1-(4-aminophenyl)pyrrolidines substituted at least in positions 2 and 3 | L'OREAL S.A. (FR) | 2004-05-06 | — | — | US | disclosed |
| EP-1341508-A1 | DYEING COMPOSITION BASED ON 1-(4-AMINOPHENYL) PYRROLIDINES SUBSTITUTED AT LEAST IN POSITIONS 2 AND 3 | L'OREAL (FR) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002045669-A1 | DYEING COMPOSITION BASED ON 1-(4-AMINOPHENYL) PYRROLIDINES SUBSTITUTED AT LEAST IN POSITIONS 2 AND 3 | L'OREAL (FR) | 2002-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040083559-A1 | Dyeing composition based on 1-(4-aminophenyl)pyrrolidines substituted at least in positions 2 and 3 | KRT18, PYCR1, COX5A | MAPT 824/4885POLB 188/4885CYP2C9 613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.