Styrene

Styrene

SCHEMBL6697336

C=Cc1ccccc1.CC(=O)C(C)=O

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.67
TSHR P16473 2/20 0.67
TDP1 Q9NUW8 2/20 0.50
AKR1C3 P42330 1/20 0.50
GLA P06280 1/20 0.50
RECQL P46063 2/20 0.47
HPGD P15428 1/20 0.45
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
AKT1 P31749 1/20 0.43
HDAC3 O15379 1/20 0.43
TNKS O95271 1/20 0.43
HDAC4 P56524 1/20 0.43
HDAC1 Q13547 1/20 0.43
HCAR2 Q8TDS4 1/20 0.43
HDAC7 Q8WUI4 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC10 Q969S8 1/20 0.43
HDAC11 Q96DB2 1/20 0.43
HDAC8 Q9BY41 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL5858997 0.93 ALDH1A1 (0.70) ALDH1A1TSHRTDP1AKR1C3GLA
Styrene SCHEMBL10614939 0.93 ALDH1A1 (0.70) ALDH1A1TSHRTDP1AKR1C3GLA
Styrene SCHEMBL385100 0.93 ALDH1A1 (0.70) ALDH1A1TSHRTDP1AKR1C3GLA
Styrene SCHEMBL9459294 0.91 ALDH1A1 (0.61) ALDH1A1TSHRTDP1AKR1C3GLA
Styrene SCHEMBL27547420 0.91 ALDH1A1 (0.67) ALDH1A1TSHRTDP1AKR1C3GLA
Styrene SCHEMBL27318228 0.91 ALDH1A1 (0.67) ALDH1A1TSHRTDP1AKR1C3GLA
Styrene SCHEMBL27529933 0.91 ALDH1A1 (0.67) ALDH1A1TSHRTDP1AKR1C3GLA
Styrene SCHEMBL10605564 0.88 ALDH1A1 (0.64) ALDH1A1TSHRTDP1AKR1C3GLA
Styrene SCHEMBL8348522 0.88 ALDH1A1 (0.64) ALDH1A1TSHRTDP1AKR1C3GLA
Styrene SCHEMBL141555 0.88 ALDH1A1 (0.64) ALDH1A1TSHRTDP1AKR1C3GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040224114-A1 Roofing system and tile ARMACELL ENTERPRISE GMBH (DE) 2004-11-11 US claimed
US-20030012946-A1 Coated polymeric foam ARMACELL ENTERPRISE GMBH (DE) 2003-01-16 US claimed
EP-1270653-A2 Coated polymeric foam Armacell Enterprise GmbH (DE) 2003-01-02 EP claimed
US-20040224114-A1 Roofing system and tile ARMACELL ENTERPRISE GMBH (DE) 2004-11-11 US disclosed
US-20030012946-A1 Coated polymeric foam ARMACELL ENTERPRISE GMBH (DE) 2003-01-16 US disclosed
EP-1270653-A2 Coated polymeric foam Armacell Enterprise GmbH (DE) 2003-01-02 EP disclosed