Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Styrene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | TSHR | P16473 | 2/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL27547420 | 0.98 | ALDH1A1 (0.67) | ALDH1A1TSHRTDP1AKR1C3GLA | |
| Styrene SCHEMBL28284709 | 0.95 | ALDH1A1 (0.64) | ALDH1A1TSHRTDP1AKR1C3GLA | |
| Styrene SCHEMBL4658487 | 0.95 | ALDH1A1 (0.64) | ALDH1A1TSHRTDP1AKR1C3GLA | |
| Styrene SCHEMBL8348522 | 0.95 | ALDH1A1 (0.64) | ALDH1A1TSHRTDP1AKR1C3GLA | |
| Styrene SCHEMBL5858997 | 0.95 | ALDH1A1 (0.70) | ALDH1A1TSHRTDP1AKR1C3GLA | |
| Styrene SCHEMBL10614939 | 0.95 | ALDH1A1 (0.70) | ALDH1A1TSHRTDP1AKR1C3GLA | |
| Styrene SCHEMBL19281746 | 0.93 | ALDH1A1 (0.61) | ALDH1A1TSHRTDP1AKR1C3GLA | |
| Styrene SCHEMBL27529933 | 0.93 | ALDH1A1 (0.67) | ALDH1A1TSHRTDP1AKR1C3GLA | |
| Styrene SCHEMBL6697336 | 0.93 | ALDH1A1 (0.67) | ALDH1A1TSHRTDP1AKR1C3GLA | |
| Styrene SCHEMBL27318228 | 0.93 | ALDH1A1 (0.67) | ALDH1A1TSHRTDP1AKR1C3GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 235 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4714752-A1 | MODIFIED INORGANIC FIBER MATERIAL AND PREPARATION METHOD THEREFOR, AUTOMOBILE ROOF LINING COMPOSITE MATERIAL, SOUND INSULATION COMPOSITE MATERIAL, AND VEHICLE | SSI New Material (Zhenjiang) Co., Ltd. (CN) | 2026-03-25 | — | — | EP | claimed |
| US-12297151-B2 | Gypsum board from gypsum having high level of chloride salt and a polymer layer and methods associated therewith | KNAUF GIPS KG (DE) | 2025-05-13 | — | — | US | claimed |
| EP-4507887-A1 | GYPSUM BOARD FROM GYPSUM HAVING HIGH LEVEL OF CHLORIDE SALT AND A POLYMER LAYER AND METHODS ASSOCIATED THEREWITH | Knauf Gips KG (DE) | 2025-02-19 | — | — | EP | claimed |
| WO-2024149252-A1 | MAGNESIUM PHOSPHATE SUBSTANCE, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USE THEREOF | 上海石趣医药科技有限公司 | 2024-07-18 | — | — | WO | claimed |
| CN-118308021-A | Ultraviolet-resistant automobile glass film and preparation method thereof | 新田县德润新材料产业园有限公司 | 2024-07-09 | — | — | CN | claimed |
| CN-117924082-A | Method and device for controlling benzene content in vinyl acetate | 内蒙古蒙维科技有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-117813077-A | Composition and method for producing the same | 西姆莱斯股份公司 | 2024-04-02 | — | — | CN | claimed |
| CN-117510397-A | Styrene acetate compound and preparation method and application thereof | 青海大学 | 2024-02-06 | — | — | CN | claimed |
| WO-2023215194-A1 | GYPSUM BOARD FROM GYPSUM HAVING HIGH LEVEL OF CHLORIDE SALT AND A POLYMER LAYER AND METHODS ASSOCIATED THEREWITH | UNITED STATES GYPSUM COMPANY (US) | 2023-11-09 | — | — | WO | claimed |
| US-20230357085-A1 | GYPSUM BOARD FROM GYPSUM HAVING HIGH LEVEL OF CHLORIDE SALT AND A POLYMER LAYER AND METHODS ASSOCIATED THEREWITH | UNITED STATES GYPSUM COMPANY (US) | 2023-11-09 | — | — | US | claimed |
| US-20090005527-A1 | PHOSPHONIC COMPOUNDS AND METHODS OF USE THEREOF | SUNTRUST BANK | 2009-01-01 | — | — | US | claimed |
| US-20070275193-A1 | Functional Materials and Novel Methods for the Fabrication of Microfluidic Devices | NATIONAL SCIENCE FOUNDATION | 2007-11-29 | — | — | US | claimed |
| JP-2007527784-A | — | — | 2007-10-04 | — | — | JP | claimed |
| EP-1737574-A2 | FUNCTIONAL MATERIALS AND NOVEL METHODS FOR THE FABRICATION OF MICROFLUIDIC DEVICES | The University of North Carolina at Chapel Hill (US) | 2007-01-03 | — | — | EP | claimed |
| WO-2005084191-A2 | FUNCTIONAL MATERIALS AND NOVEL METHODS FOR THE FABRICATION OF MICROFLUIDIC DEVICES | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2005-09-15 | — | — | WO | claimed |
| CN-1139131-A | Mixture of polymers including halogen-containing polymer and compatibilized with grafted aliphatic polyester | ATOCHEM ELF SA (FR) | 1997-01-01 | — | — | CN | claimed |
| US-4820683-A | COLORFASTNESS | APPLETON PAPERS INC. (US) | 1989-04-11 | — | — | US | claimed |
| EP-0119713-B1 | LIQUID ELECTROGRAPHIC DEVELOPERS | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1987-10-07 | — | — | EP | claimed |
| US-4547449-A | IMPROVED REPLENISHABILITY | EASTMAN KODAK COMPANY (US) | 1985-10-15 | — | — | US | claimed |
| EP-0119713-A1 | Liquid electrographic developers | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1984-09-26 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005527-A1 | PHOSPHONIC COMPOUNDS AND METHODS OF USE THEREOF | PHOSPHO1, PPIP5K2, FASN | ALDH1A1 3501/4885TSHR 4765/4885TDP1 2919/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.