SCHEMBL6697342

SCHEMBL6697342

Cc1nc2c(Cc3ccccc3)cccc2[nH]1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.50
DRD4 P21917 1/20 0.50
DRD3 P35462 1/20 0.50
GAA P10253 1/20 0.46
PARP1 P09874 1/20 0.45
HTR6 P50406 2/20 0.45
ALKBH3 Q96Q83 1/20 0.44
ATP4A P20648 1/20 0.42
ATP4B P51164 1/20 0.42
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
GRIN1 Q05586 1/20 0.41
GRIN2B Q13224 1/20 0.41
ALDH1A1 P00352 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
ESR1 P03372 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11198298 0.86 MGAM (0.48) DRD2DRD4DRD3GAAPARP1
SCHEMBL12109685 0.81 LMNA (0.49) DRD2DRD4DRD3GAAPARP1
SCHEMBL5071826 0.81 PNP (0.52) GAACYP3A4ALDH1A1MEN1KMT2A
SCHEMBL9306184 0.81 GAA (0.42) GAAHTR6ALKBH3CYP1A2CYP3A4
SCHEMBL9307952 0.81 NPC1 (0.46) GAAHTR6ALKBH3CYP1A2CYP3A4
SCHEMBL8263596 0.80 PARP1 (0.54) DRD2DRD4DRD3GAAPARP1
SCHEMBL5788740 0.80 PARP1 (0.54) DRD2DRD4DRD3PARP1ATP4A
SCHEMBL8816937 0.79 CYP1A2 (0.59) GAAPARP1CYP1A2CYP2D6GRIN2B
SCHEMBL12109694 0.79 CYP1A2 (0.55) DRD2DRD4DRD3CYP1A2CYP2D6
SCHEMBL7981913 0.79 DRD2 (0.49) DRD2DRD4DRD3PARP1HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016044636-A2 METHOD FOR PRODUCING BENZAZOLOQUINOLIUM (BQS) SALTS AND USING THE BIOLOGICAL ACTIVITY OF THE COMPOSITION SISTEMA UNIVERSITARIO ANA G. MENDEZ, INC. (US) 2016-03-24 WO disclosed
WO-2004078874-A2 NOVEL DYE COMPLEXES AND USE THEREOF IN IMAGING MEMBERS AND METHODS POLAROID CORPORATION (US) 2004-09-16 WO disclosed