Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.40 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4705539 | 1.00 | GABRR1 (0.45) | GABRR1LMNATHRBBLMKMT2A | |
| SCHEMBL1640046 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL2708490 | 0.92 | BLM (0.43) | GABRR1LMNATHRBBLMKMT2A | |
| SCHEMBL5067741 | 0.87 | TSHR (0.39) | GABRR1LMNATHRBBLMKMT2A | |
| SCHEMBL30593457 | 0.87 | GABRR1 (0.65) | GABRR1LMNATHRBBLMKMT2A | |
| SCHEMBL251587 | 0.87 | TSHR (0.39) | GABRR1LMNATHRBBLMKMT2A | |
| SCHEMBL16585471 | 0.87 | GABRR1 (0.65) | GABRR1LMNATHRBBLMKMT2A | |
| SCHEMBL28517809 | 0.87 | GABRR1 (0.65) | GABRR1LMNATHRBBLMKMT2A | |
| SCHEMBL23438057 | 0.85 | TDP1 (0.47) | GABRR1LMNATHRBBLMKMT2A | |
| SCHEMBL5860126 | 0.85 | ALDH1A1 (0.56) | GABRR1LMNATHRBBLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040253184-A1 | Targeted polymerized liposome diagnostic and treatment agents | TARGESOME, INC. | 2004-12-16 | — | — | US | disclosed |
| US-6569451-B1 | Hydrophilic head group of lipid and liposome-forming lipid and a bifunctional linker; polymerizable tail; metal diethylene-triamine pentaacetic acid chelate is head and bifunctional linker is polyethylene glycol, propylene glycol or polyglycine | TARGESOME, INC. | 2003-05-27 | — | — | US | disclosed |
| US-20020071843-A1 | Targeted therapeutic agents | TARGESOME, INC. | 2002-06-13 | — | — | US | disclosed |
| US-6350466-B1 | COMPOSITION COMPRISING PARTICLES EACH COMPRISING SHEET CONTAINING LIPIDS WITH HYDROPHOBIC TAIL GROUP COVALENTLY CROSSLINKED WITH THAT OF ADJACENT LIPID, EACH PARTICLE FURTHER COMPRISING TARGETING AGENT AND SUBSTANCE FOR DELIVERY | TARGESOME, INC. | 2002-02-26 | — | — | US | disclosed |
| US-6132764-A | MAGNETIC RESONANCE IMAGING SIGNAL ENHANCEMENT OF TARGETED CELLS, LIVER AND KIDNEY; IN VIVO STABILITY; DIAGNOSING ABNORMAL PATHOLOGY; TARGETING DELIVERY POLYMERIZED LIPOSOME PARTICLES TARGETED TO MOLECULE AT OR NEAR SITE OF TREATMENT | TARGESOME, INC. (US) | 2000-10-17 | — | — | US | disclosed |
| US-6090408-A | Use of polymerized lipid diagnostic agents | TARGESOME, INC. (US) | 2000-07-18 | — | — | US | disclosed |
| US-5512294-A | MEDICAL DIAGNOSIS, IMAGING | NANOVALENT PHARMACEUTICALS, INC. | 1996-04-30 | — | — | US | disclosed |