SCHEMBL669741

SCHEMBL669741

C#COC(=O)Oc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.42
ATM Q13315 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
ALOX15 P16050 2/20 0.41
HPGD P15428 1/20 0.41
HSD17B10 Q99714 1/20 0.41
ALDH1A1 P00352 3/20 0.41
MAPT P10636 3/20 0.41
ELANE P08246 2/20 0.40
USP2 O75604 1/20 0.39
KDM4E B2RXH2 1/20 0.39
NSD2 O96028 1/20 0.39
GAA P10253 1/20 0.39
PPARG P37231 1/20 0.37
KMT2A Q03164 1/20 0.37
NCOA2 Q15596 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
RXFP1 Q9HBX9 1/20 0.37
FABP7 O15540 1/20 0.37
FABP5 Q01469 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14775151 0.80 LMNA (0.53) L3MBTL1ALDH1A1MAPTUSP2GAA
Ethyne SCHEMBL168883 0.80 TDP1 (0.50) TDP1ATML3MBTL1ALOX15HPGD
SCHEMBL27352197 0.79 TDP1 (0.54) TDP1ATML3MBTL1ALOX15HPGD
SCHEMBL9353461 0.79 TDP1 (0.54) TDP1ATML3MBTL1ALOX15HPGD
SCHEMBL9353455 0.79 TDP1 (0.54) TDP1ATML3MBTL1ALOX15HPGD
SCHEMBL18073 0.79 TDP1 (0.54) TDP1ATML3MBTL1ALOX15HPGD
SCHEMBL9241160 0.79 TDP1 (0.54) TDP1ATML3MBTL1ALOX15HPGD
SCHEMBL3952264 0.79 TDP1 (0.42) TDP1ATML3MBTL1ALOX15HPGD
SCHEMBL14775344 0.78 LMNA (0.59) ALOX15HSD17B10ALDH1A1MAPTGAA
Cyanide SCHEMBL10956106 0.78 TDP1 (0.48) TDP1ATML3MBTL1ALOX15HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2189443-B1 TRICYCLIC AMIDE COMPOUND RES FOUND ITSUU LAB (JP) 2013-10-23 EP claimed
EP-0378604-B1 1,1-DIOXO-CEPHEM-4-CARBOTHIOLIC ACID DERIVATIVES ERBA CARLO SPA (IT) 1994-03-02 EP claimed
US-20240274855-A1 HIGH ENERGY DENSITY REDOX FLOW DEVICE MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2024-08-15 US disclosed
EP-2606529-B1 ELECTROCHEMICAL CELL MASSACHUSETTS INST TECHNOLOGY (US) 2022-11-23 EP disclosed
US-20180034090-A1 HIGH ENERGY DENSITY REDOX FLOW DEVICE MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2018-02-01 US disclosed
US-9786944-B2 High energy density redox flow device MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2017-10-10 US disclosed
EP-2514013-B1 HIGH ENERGY DENSITY REDOX FLOW DEVICE MASSACHUSETTS INST TECHNOLOGY (US) 2017-05-17 EP disclosed
US-8722227-B2 High energy density redox flow device MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2014-05-13 US disclosed
US-20130344367-A1 HIGH ENERGY DENSITY REDOX FLOW DEVICE 24-M Technologies, Inc. (US) 2013-12-26 US disclosed
EP-2606529-A1 STATIONARY, FLUID REDOX ELECTRODE Massachusetts Institute Of Technology (US) 2013-06-26 EP disclosed
EP-2514013-A2 HIGH ENERGY DENSITY REDOX FLOW DEVICE Massachusetts Institute of Technology (US) 2012-10-24 EP disclosed
US-20120164499-A1 STATIONARY, FLUID REDOX ELECTRODE MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2012-06-28 US disclosed
WO-2012024499-A1 STATIONARY, FLUID REDOX ELECTRODE MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2012-02-23 WO disclosed
US-20110274948-A1 ENERGY TRANSFER USING ELECTROCHEMICALLY ISOLATED FLUIDS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2011-11-10 US disclosed
WO-2011127384-A1 ENERGY TRANSFER USING ELECTROCHEMICALLY ISOLATED FLUIDS MASSACHUSSETTS INSTITUTE OF TECHNOLOGY (US) 2011-10-13 WO disclosed
US-20110200848-A1 HIGH ENERGY DENSITY REDOX FLOW DEVICE MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2011-08-18 US disclosed
WO-2011084649-A2 HIGH ENERGY DENSITY REDOX FLOW DEVICE MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2011-07-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110200848-A1 HIGH ENERGY DENSITY REDOX FLOW DEVICE NOX4, CYBB, NOX1 TDP1 3499/4885ATM 2762/4885L3MBTL1 4443/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.