SCHEMBL6697515

SCHEMBL6697515

O=[N+]([O-])c1cccc(C#CCCO)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.54
HSP90AA1 P07900 2/20 0.54
MAPT P10636 2/20 0.54
HTT P42858 2/20 0.54
NPSR1 Q6W5P4 2/20 0.54
S1PR2 O95136 1/20 0.54
OPRK1 P41145 1/20 0.54
FFAR1 O14842 1/20 0.52
TSHR P16473 5/20 0.48
LMNA P02545 2/20 0.48
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
MITF O75030 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
ALOX15 P16050 1/20 0.46
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
CHRM2 P08172 1/20 0.43
CHRM1 P11229 1/20 0.43
ASIC3 Q9UHC3 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1312435 0.91 ALDH1A1 (0.51) ALDH1A1HSP90AA1MAPTHTTNPSR1
SCHEMBL6690856 0.90 ALDH1A1 (0.50) ALDH1A1HSP90AA1MAPTHTTNPSR1
SCHEMBL6690094 0.88 ALDH1A1 (0.49) ALDH1A1HSP90AA1MAPTHTTNPSR1
SCHEMBL6692873 0.87 ALDH1A1 (0.56) ALDH1A1HSP90AA1MAPTHTTNPSR1
SCHEMBL22301347 0.84 ALDH1A1 (0.50) ALDH1A1HSP90AA1MAPTHTTNPSR1
SCHEMBL6690776 0.84 FFAR1 (0.66) ALDH1A1HSP90AA1MAPTHTTNPSR1
SCHEMBL6682672 0.82 ALDH1A1 (0.48) ALDH1A1HSP90AA1MAPTHTTNPSR1
SCHEMBL28728423 0.81 TSHR (0.67) ALDH1A1HSP90AA1MAPTHTTNPSR1
SCHEMBL6689389 0.80 ALDH1A1 (0.50) ALDH1A1HSP90AA1MAPTHTTNPSR1
SCHEMBL22398101 0.80 TSHR (0.50) ALDH1A1HSP90AA1MAPTNPSR1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107365254-B Application of polymer microspheres in Raman detection 北京大学 2021-06-04 CN disclosed
WO-2004106292-A1 HALOETHYL UREA COMPOUNDS AND THEIR USE TO ATTENUATE, INHIBIT OR PREVENT NON-CANCEROUS PATHOGENIC CELLULAR PROLIFERATION AND DISEASES ASSOCIATED THEREWITH IMOTEP INC. (CA) 2004-12-09 WO disclosed
WO-2004106291-A1 HALOETHYL UREA COMPOUNDS AND THE USE THEREOF TO ATTENUATE, INHIBIT OR PREVENT CANCER CELL MIGRATION IMOTEP INC. (CA) 2004-12-09 WO disclosed