SCHEMBL6697595

SCHEMBL6697595

CCS(=O)(=O)N(C(=O)c1ccc(OC)cc1)c1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1C#N

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.36
POLB P06746 1/20 0.36
NPC1 O15118 1/20 0.33
LMNA P02545 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
BCAT2 O15382 7/20 0.33
BCAT1 P54687 7/20 0.33
ALDH1A1 P00352 1/20 0.31
S1PR3 Q99500 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7911705 0.91 BCAT2 (0.32) BCAT2BCAT1
SCHEMBL6699122 0.85 BCAT2 (0.33) BCAT2BCAT1
SCHEMBL6693153 0.85 BCAT2 (0.33) BCAT2BCAT1
SCHEMBL6703631 0.84 BCAT2 (0.33) BCAT2BCAT1
SCHEMBL6702752 0.84 BCAT2 (0.33) MAPTPOLBNPC1LMNARAB9A
SCHEMBL6699525 0.84 BCAT2 (0.32) BCAT2BCAT1
SCHEMBL6693966 0.84 BCAT2 (0.32) BCAT2BCAT1
SCHEMBL7923907 0.83 BCAT2 (0.32) BCAT2BCAT1
SCHEMBL6697260 0.83 BCAT2 (0.33) BCAT2BCAT1
SCHEMBL6697287 0.82 BCAT2 (0.35) BCAT2BCAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040171488-A1 N-aryl-uracils based Herbicides FEUCHT DIETER (DE) 2004-09-02 US claimed
US-6734139-B1 N-aryl-uracile-based herbicides BAYER AKTIENGESELLSCHAFT (DE) 2004-05-11 US claimed
US-20040171488-A1 N-aryl-uracils based Herbicides FEUCHT DIETER (DE) 2004-09-02 US disclosed
US-6734139-B1 N-aryl-uracile-based herbicides BAYER AKTIENGESELLSCHAFT (DE) 2004-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171488-A1 N-aryl-uracils based Herbicides DDT, UNG, DDC MAPT 3439/4885POLB 962/4885NPC1 4564/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.