Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanidine SCHEMBL66976 | 1.00 | — | — | |
| Guanidine SCHEMBL28214584 | 1.00 | — | — | |
| Guanidine SCHEMBL20138497 | 1.00 | NOS2 (0.39) | — | |
| Guanidine SCHEMBL30875702 | 1.00 | NOS2 (0.39) | — | |
| Guanidine SCHEMBL27595748 | 0.94 | — | — | |
| Guanidine SCHEMBL9397537 | 0.94 | — | — | |
| Guanidine SCHEMBL28214616 | 0.94 | — | — | |
| Guanidine SCHEMBL15816733 | 0.94 | — | — | |
| Guanidine SCHEMBL7265251 | 0.94 | — | — | |
| Guanidine SCHEMBL28107159 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1533 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12594224-B2 | Oral care compositions and methods of use | COLGATE-PALMOLIVE COMPANY (US) | 2026-04-07 | — | — | US | claimed |
| EP-4637930-A1 | PROCESS FOR DYEING KERATIN HAIR FIBERS COMPRISING THE APPLICATION OF A TREATMENT WITH AN ALKALINE AGENT AND OF A COMPOSITION COMPRISING A (POLY)CARBODIIMIDE COMPOUND AND A COLOURING AGENT | L'OREAL (FR) | 2025-10-29 | — | — | EP | claimed |
| US-12355050-B2 | Components and systems to manage thermal runaway issues in electric vehicle batteries | ASPEN AEROGELS, INC. (US) | 2025-07-08 | — | — | US | claimed |
| CN-118401228-A | Oral care compositions and methods of use | 高露洁-棕榄公司 | 2024-07-26 | — | — | CN | claimed |
| CN-115297824-B | Oral care compositions and methods of use | 高露洁-棕榄公司 | 2024-07-19 | — | — | CN | claimed |
| US-20240216241-A1 | Oral Care Compositions and Methods of Use | COLGATE-PALMOLIVE COMPANY (US) | 2024-07-04 | — | — | US | claimed |
| WO-2024133716-A1 | PROCESS FOR DYEING KERATIN HAIR FIBERS COMPRISING THE APPLICATION OF A TREATMENT WITH AN ALKALINE AGENT AND OF A COMPOSITION COMPRISING A (POLY)CARBODIIMIDE COMPOUND AND A COLOURING AGENT | L'OREAL (FR) | 2024-06-27 | — | — | WO | claimed |
| EP-4387580-A1 | ORAL CARE COMPOSITIONS COMPRISING GUANIDINE AND STANNOUS ION SOURCE AND METHODS | Colgate-Palmolive Company (US) | 2024-06-26 | — | — | EP | claimed |
| EP-4387741-A1 | ORAL CARE COMPOSITIONS AND METHODS OF USE | Colgate-Palmolive Company (US) | 2024-06-26 | — | — | EP | claimed |
| CN-117999055-A | Oral care compositions and methods comprising guanidine and stannous ion sources | 高露洁-棕榄公司 | 2024-05-07 | — | — | CN | claimed |
| US-4605018-A | Method of treating hair and anhydrous composition related thereto | CARSON PRODUCTS COMPANY (US) | 1986-08-12 | — | — | US | claimed |
| US-4589997-A | Process for preparing colloidal solution of antimony pentoxide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1986-05-20 | — | — | US | claimed |
| EP-0134708-A2 | Process for preparing colloidal solution of antimony pentoxide | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1985-03-20 | — | — | EP | claimed |
| US-4416296-A | GUANIDINE HYDROXIDE | CARSON PRODUCTS COMPANY (US) | 1983-11-22 | — | — | US | claimed |
| US-4373540-A | USING GUANIDINE HYDROXIDE; PERMANENT WAVES; NONCURING; SENSITIVITY | CARSON PRODUCTS COMPANY (US) | 1983-02-15 | — | — | US | claimed |
| US-4324263-A | GUANIDINE SALT, ALKALINE EARTH HYDROXIDE | CARSON PRODUCTS COMPANY (US) | 1982-04-13 | — | — | US | claimed |
| US-4314572-A | CURING, STRAIGHTENING, GUANIDINE HYDROXIDE | CARSON PRODUCTS COMPANY (US) | 1982-02-09 | — | — | US | claimed |
| US-4304244-A | USING GUANIDINE HYDROXIDE PREPARED FROM CALCIUM HYDROXIDE AND GUANIDINE CARBONATE; PERMANENT WAVES | CARSON PRODUCTS COMPANY (US) | 1981-12-08 | — | — | US | claimed |
| US-4303085-A | STRAIGHTENING WITH GUANIDINE SALT | CARSON PRODUCTS COMPANY (US) | 1981-12-01 | — | — | US | claimed |
| WO-1980001038-A1 | HAIR STRAIGHTENING PROCESS AND HAIR CURLING PROCESS AND COMPOSITION THEREFOR | CARSON PROD CO | 1980-05-29 | — | — | WO | claimed |