Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.42 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6698821 | 0.89 | AKR1C3 (0.53) | SMN1; SMN2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6703941 | 0.82 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL25666676 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6707021 | 0.81 | ALDH1A1 (0.46) | ALDH1A1KDM4EADCY10MAPTRAB9A | |
| SCHEMBL5365179 | 0.79 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL4002932 | 0.78 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6499184 | 0.76 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL23242577 | 0.75 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL29893548 | 0.75 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL5346355 | 0.74 | MEN1 (0.53) | SMN1; SMN2ALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040002493-A1 | Benzoic acid derivatives and pharmaceutical agents comprising the same as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-01-01 | — | — | US | disclosed |
| EP-1314719-A1 | BENZOIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-05-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040002493-A1 | Benzoic acid derivatives and pharmaceutical agents comprising the same as active ingredient | PTGER1, PTGER4, PTGES | SMN1; SMN2 3341/4885ALDH1A1 408/4885KDM4E 2162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.