Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.73 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.73 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.73 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 6/20 | 0.44 |
| ▸ | PPARD | Q03181 | 6/20 | 0.44 |
| ▸ | PPARA | Q07869 | 6/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18095273 | 1.00 | GPR84 (0.73) | GPR84FFAR1FFAR4GAACAMK2A | |
| SCHEMBL8651891 | 1.00 | GPR84 (0.73) | GPR84FFAR1FFAR4GAACAMK2A | |
| SCHEMBL28794545 | 1.00 | GPR84 (0.73) | GPR84FFAR1FFAR4GAACAMK2A | |
| SCHEMBL7860967 | 1.00 | GPR84 (0.73) | GPR84FFAR1FFAR4GAACAMK2A | |
| SCHEMBL6367323 | 1.00 | GPR84 (0.73) | GPR84FFAR1FFAR4GAACAMK2A | |
| SCHEMBL6551117 | 1.00 | GPR84 (0.73) | GPR84FFAR1FFAR4GAACAMK2A | |
| SCHEMBL580749 | 1.00 | GPR84 (0.73) | GPR84FFAR1FFAR4GAACAMK2A | |
| SCHEMBL7767501 | 0.95 | GPR84 (0.65) | GPR84FFAR1FFAR4GAACAMK2A | |
| SCHEMBL3262578 | 0.95 | GPR84 (0.65) | GPR84FFAR1FFAR4GAACAMK2A | |
| SCHEMBL7765618 | 0.95 | GPR84 (0.65) | GPR84FFAR1FFAR4GAACAMK2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5717111-A | Process for the continuous preparation of macrocyclic compounds | HUELS AKTIENGESELLSCHAFT (DE) | 1998-02-10 | — | — | US | claimed |
| US-20250188501-A1 | SEMISYNTHETIC ROUTES TO ORGANIC COMPOUNDS | AGAIN BIO APS (DK) | 2025-06-12 | — | — | US | disclosed |
| US-12188068-B2 | Semisynthetic routes to organic compounds | GENOMATICA, INC. (US) | 2025-01-07 | — | — | US | disclosed |
| US-20210310033-A1 | SEMISYNTHETIC ROUTES TO ORGANIC COMPOUNDS | AGAIN BIO APS (DK) | 2021-10-07 | — | — | US | disclosed |
| US-11008597-B2 | Chemo-enzymatic process | GENOMATICA, INC. (US) | 2021-05-18 | — | — | US | disclosed |
| EP-3739057-A1 | SEMISYNTHETIC ROUTES TO ORGANIC COMPOUNDS | Genomatica, Inc. (US) | 2020-11-18 | — | — | EP | disclosed |
| EP-3129492-B1 | CHEMO-ENZYMATIC PROCESS FOR THE PREPARATION OF LACTONES AND MACROCYCLIC KETONES | GENOMATICA INC (US) | 2020-06-03 | — | — | EP | disclosed |
| EP-3129492-A1 | SEMISYNTHETIC ROUTES TO ORGANIC COMPOUNDS | REG Life Sciences, LLC (US) | 2017-02-15 | — | — | EP | disclosed |
| US-20170029854-A1 | SEMISYNTHETIC ROUTES TO ORGANIC COMPOUNDS | REG Life Sciences, LLC (US) | 2017-02-02 | — | — | US | disclosed |
| CN-106164282-A | Semisynthetic route to organic compounds | REG生命科学有限责任公司 | 2016-11-23 | — | — | CN | disclosed |
| WO-2015157719-A1 | SEMISYNTHETIC ROUTES TO ORGANIC COMPOUNDS | REG Life Sciences, LLC (US) | 2015-10-15 | — | — | WO | disclosed |
| JP-2004244397-A | METHOD FOR PRODUCING OXALIDE | MITSUI CHEMICALS INC | 2004-09-02 | — | — | JP | disclosed |
| JP-2003321465-A | METHOD FOR PRODUCING OXALIDE | MITSUI CHEMICALS INC | 2003-11-11 | — | — | JP | disclosed |
| US-5717111-A | Process for the continuous preparation of macrocyclic compounds | HUELS AKTIENGESELLSCHAFT (DE) | 1998-02-10 | — | — | US | disclosed |
| EP-0260680-B1 | Improved process for the production of macrocyclic esters by the depolymerization of polyesters | HENKEL CORP (US) | 1993-10-27 | — | — | EP | disclosed |
| EP-0260680-A2 | Improved process for the production of macrocyclic esters by the depolymerization of polyesters | HENKEL CORPORATION (US) | 1988-03-23 | — | — | EP | disclosed |
| US-4709058-A | Process for the production of macrocyclic esters by the depolymerization of polyesters | NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) | 1987-11-24 | — | — | US | disclosed |
| US-4594434-A | Macrocyclic compounds | NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) | 1986-06-10 | — | — | US | disclosed |
| US-4499288-A | THERMAL DEPOLYMERIZATION OF POLYESTERS; EFFICIENCY | NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) | 1985-02-12 | — | — | US | disclosed |
| US-4393223-A | THERMAL DEPOLYMERIZATION OF POLYESTERS | EMERY INDUSTRIES, INC. (US) | 1983-07-12 | — | — | US | disclosed |