SCHEMBL580749

SCHEMBL580749

O=C(O)CCCCCCCCCCCCCCCCCOCCCCCCCCCCCCCCCCCCO

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 6/20 0.73
FFAR1 O14842 2/20 0.73
FFAR4 Q5NUL3 2/20 0.73
GAA P10253 1/20 0.60
CAMK2A Q9UQM7 1/20 0.56
ALDH1A1 P00352 4/20 0.56
TSHR P16473 6/20 0.55
LMNA P02545 3/20 0.55
NFKB1 P19838 1/20 0.55
PMP22 Q01453 1/20 0.55
FNTA P49354 1/20 0.45
FNTB P49356 1/20 0.45
PPARG P37231 6/20 0.44
PPARD Q03181 6/20 0.44
PPARA Q07869 6/20 0.44
HDAC11 Q96DB2 5/20 0.44
TLR2 O60603 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
MEN1 O00255 2/20 0.44
FABP4 P15090 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6697760 1.00 GPR84 (0.73) GPR84FFAR1FFAR4GAACAMK2A
SCHEMBL18095273 1.00 GPR84 (0.73) GPR84FFAR1FFAR4GAACAMK2A
SCHEMBL8651891 1.00 GPR84 (0.73) GPR84FFAR1FFAR4GAACAMK2A
SCHEMBL28794545 1.00 GPR84 (0.73) GPR84FFAR1FFAR4GAACAMK2A
SCHEMBL7860967 1.00 GPR84 (0.73) GPR84FFAR1FFAR4GAACAMK2A
SCHEMBL6367323 1.00 GPR84 (0.73) GPR84FFAR1FFAR4GAACAMK2A
SCHEMBL6551117 1.00 GPR84 (0.73) GPR84FFAR1FFAR4GAACAMK2A
SCHEMBL7767501 0.95 GPR84 (0.65) GPR84FFAR1FFAR4GAACAMK2A
SCHEMBL3262578 0.95 GPR84 (0.65) GPR84FFAR1FFAR4GAACAMK2A
SCHEMBL7765618 0.95 GPR84 (0.65) GPR84FFAR1FFAR4GAACAMK2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 749 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023208523-A1 COMPOSITION WITH A POLYPHENOL, AN AQUEOUS DISPERSION OF WAX, A NONIONIC SURFACTANT WITH AN HLB OF GREATER THAN OR EQUAL TO 8 AND AN UNCOATED IRON OXIDE L'OREAL (FR) 2023-11-02 WO claimed
EP-2863996-B1 LIQUID COSMETIC COMPOSITION COMPRISING AN OIL, HYDROPHOBIC SILICA AEROGEL PARTICLES AND A WAX WITH A MELTING POINT OF GREATER THAN 60°C OREAL (FR) 2021-03-24 EP claimed
US-20200093717-A1 EXFOLIATING AND HYDRATING MAKEUP REMOVING COMPOSITIONS L'OREAL (FR) 2020-03-26 US claimed
US-10576031-B1 Exfoliating and hydrating makeup removing compositions L'OREAL (FR) 2020-03-03 US claimed
US-10470997-B2 Liquid cosmetic composition comprising an oil, hydrophobic silica aerogel particles and a wax with a melting point of greater than 60° celsius L'OREAL (FR) 2019-11-12 US claimed
EP-1920757-B1 Cosmetic composition containing citric acid derivatives ORÉAL L (FR) 2016-05-11 EP claimed
US-20150164775-A1 LIQUID COSMETIC COMPOSITION COMPRISING AN OIL, HYDROPHOBIC SILICA AEROGEL PARTICLES AND A WAX WITH A MELTING POINT OF GREATER THAN 60 DEGREES CELSIUS L'OREAL (FR) 2015-06-18 US claimed
EP-2863996-A1 LIQUID COSMETIC COMPOSITION COMPRISING AN OIL, HYDROPHOBIC SILICA AEROGEL PARTICLES AND A WAX WITH A MELTING POINT OF GREATER THAN 60°C L'Oréal (FR) 2015-04-29 EP claimed
WO-2013190129-A1 LIQUID COSMETIC COMPOSITION COMPRISING AN OIL, HYDROPHOBIC SILICA AEROGEL PARTICLES AND A WAX WITH A MELTING POINT OF GREATER THAN 60°C L'OREAL (FR) 2013-12-27 WO claimed
WO-2012171872-A2 EMULSION-TYPE COSMETIC COMPOSITION FOR COATING KERATIN FIBRES, AND PROCESS FOR COATING KERATIN FIBRES L'OREAL (FR) 2012-12-20 WO claimed
EP-2168563-A2 Eyelash make-up composition and packaging system L'OREAL (FR) 2010-03-31 EP claimed
EP-2168562-A1 Eyelash make-up composition and packaging system L'OREAL (FR) 2010-03-31 EP claimed
WO-2010010306-A2 COSMETIC HEAT TREATMENT METHOD USING COMPOSITION HAVING A LOW OIL CONTENT L'OREAL (FR) 2010-01-28 WO claimed
EP-1534219-B1 MAKE-UP COMPOSITION FOR KERATIN FIBRES SUCH AS EYELASHES OREAL (FR) 2009-12-16 EP claimed
WO-2009080955-A2 COSMETIC MAKE-UP AND/OR CARE METHOD USING A SILOXANE RESIN AND A POLAR WAX L'OREAL (FR) 2009-07-02 WO claimed
EP-1552806-B1 Long lasting make-up composition for keratin fibers OREAL (FR) 2008-09-10 EP claimed
EP-1870075-A1 Mascara comprising at least 21% of wax and a filler L'Oréal (FR) 2007-12-26 EP claimed
EP-1424059-B1 Cosmetic composition comprising a tacky wax OREAL (FR) 2006-06-07 EP claimed
US-20060099231-A1 Make-up composition for keratin fibres such as eyelashes L'OREAL S.A. (FR) 2006-05-11 US claimed
US-20050180936-A1 Keratin fiber make-up composition with long-term stability L'OREAL S.A. (FR) 2005-08-18 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10470997-B2 Liquid cosmetic composition comprising an oil, hydrophobic silica aerogel particles and a wax with a melting point of greater than 60° celsius CUTA, IL33, LSS GPR84 1168/4885FFAR1 3479/4885FFAR4 3886/4885
US-20050180936-A1 Keratin fiber make-up composition with long-term stability KRT18, DSG1, DSP GPR84 4539/4885FFAR1 3767/4885FFAR4 3882/4885
US-20150164775-A1 LIQUID COSMETIC COMPOSITION COMPRISING AN OIL, HYDROPHOBIC SILICA AEROGEL PARTICLES AND A WAX WITH A MELTING POINT OF GREATER THAN 60 DEGREES CELSIUS CUTA, IL33, LIPA GPR84 948/4885FFAR1 2678/4885FFAR4 3356/4885
US-20200093717-A1 EXFOLIATING AND HYDRATING MAKEUP REMOVING COMPOSITIONS DSG1, AQP3, AQP1 GPR84 3087/4885FFAR1 520/4885FFAR4 502/4885
US-20060099231-A1 Make-up composition for keratin fibres such as eyelashes KRT18, DSG1, CUTA GPR84 935/4885FFAR1 2416/4885FFAR4 3212/4885
US-10576031-B1 Exfoliating and hydrating makeup removing compositions DSG1, AQP3, AQP1 GPR84 3087/4885FFAR1 520/4885FFAR4 502/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.