Acetic Acid

Acetic Acid

SCHEMBL6697879

C=Cc1ccc(C=CC(=O)O)cc1.CC(=O)O

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 known ✓ P03372 2/20 0.59
ESR2 known ✓ Q92731 2/20 0.59
AGTR1 known ✓ P30556 1/20 0.48
HCAR2 Q8TDS4 3/20 0.59
CA12 O43570 3/20 0.59
CA1 P00915 3/20 0.59
CA2 P00918 3/20 0.59
CA3 P07451 3/20 0.59
CA4 P22748 3/20 0.59
CA6 P23280 3/20 0.59
CA5A P35218 3/20 0.59
CA7 P43166 3/20 0.59
CA9 Q16790 3/20 0.59
CA14 Q9ULX7 3/20 0.59
CA5B Q9Y2D0 3/20 0.59
AKR1B10 O60218 3/20 0.59
AKR1B1 P15121 3/20 0.59
DPP4 P27487 2/20 0.59
PKM P14618 2/20 0.59
TYR P14679 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL175545 0.94 HCAR2 (0.65) HCAR2CA12CA1CA2CA3
SCHEMBL14107508 0.94 HCAR2 (0.65) HCAR2CA12CA1CA2CA3
SCHEMBL5707299 0.94 HCAR2 (0.65) HCAR2CA12CA1CA2CA3
SCHEMBL3633625 0.89 FOS (0.56) HCAR2CA12CA1CA2CA3
SCHEMBL3633623 0.89 FOS (0.56) HCAR2CA12CA1CA2CA3
SCHEMBL10717246 0.88 HCAR2 (0.59) HCAR2CA12CA1CA2CA3
Cinnamic Acid SCHEMBL10919255 0.86 HCAR2 (0.79) HCAR2CA12CA1CA2CA3
Cinnamic Acid SCHEMBL22283529 0.86 HCAR2 (0.79) HCAR2CA12CA1CA2CA3
SCHEMBL713717 0.82 HCAR2 (0.81) HCAR2CA12CA1CA2CA3
SCHEMBL68395 0.82 HCAR2 (0.81) HCAR2CA12CA1CA2CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9217920-B2 Photocurable compositions 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-12-22 US disclosed
US-20150248055-A1 PHOTOCURABLE COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-09-03 US disclosed
EP-2892938-A1 PHOTOCURABLE COMPOSITIONS 3M Innovative Properties Company (US) 2015-07-15 EP disclosed
EP-2883109-A1 PHOTOCURABLE COMPOSITIONS 3M Innovative Properties Company (US) 2015-06-17 EP disclosed
EP-2812758-A1 PHOTOCURABLE COMPOSITION 3M Innovative Properties Company (US) 2014-12-17 EP disclosed
US-8883402-B2 Photocurable compositions 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-11-11 US disclosed
US-8715904-B2 Photocurable composition 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-05-06 US disclosed
US-8703385-B2 Photoresist composition 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-04-22 US disclosed
US-20140048741-A1 FILTRATION MEDIA 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-02-20 US disclosed
WO-2014025498-A1 PHOTOCURABLE COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-02-13 WO disclosed
EP-0915736-B1 FILTER SHEET AND PROCESS FOR PURIFYING PHOTORESIST COMPOSITION EMPLOYING THE FILTER SHEET CUNO INC (US) 2003-10-15 EP disclosed
US-6576139-B1 Comprising self-supporting cellulose fibers immobilized with particulate cation exchange resin 3M INNOVATIVE PROPERTIES COMPANY 2003-06-10 US disclosed
US-20030047507-A1 Filter sheet and process for purifying photoresist composition employing the filter sheet 3M INNOVATIVE PROPERTIES COMPANY 2003-03-13 US disclosed
WO-2002000325-A2 FILTER SHEET AND PROCESS FOR PURIFYING PHOTORESIST COMPOSITION EMPLOYING THE FILTER SHEET CUNO INCORPORATED (US) 2002-01-03 WO disclosed
US-6103122-A FILTRATION OF PHOTORESISTS AND SELF-SUPPORTING FIBER MATRICES CUNO INCORPORATED (US) 2000-08-15 US disclosed
EP-0915736-A1 FILTER SHEET AND PROCESS FOR PURIFYING PHOTORESIST COMPOSITION EMPLOYING THE FILTER SHEET Cuno Incorporated (US) 1999-05-19 EP disclosed
WO-1998004348-A1 FILTER SHEET AND PROCESS FOR PURIFYING PHOTORESIST COMPOSITION EMPLOYING THE FILTER SHEET CUNO INCORPORATED (US) 1998-02-05 WO disclosed
US-5525315-A Process for removing heavy metal ions with a chelating cation exchange resin SHIPLEY COMPANY, L.L.C. (US) 1996-06-11 US disclosed
US-5518628-A Purification process SHIPLEY COMPANY INC. (US) 1996-05-21 US disclosed
US-5350714-A Point-of-use purification SHIPLEY COMPANY INC. (US) 1994-09-27 US disclosed