SCHEMBL3633625

SCHEMBL3633625

C=Cc1ccc(C)cc1.Cc1ccc(C=CC(=O)O)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOS P01100 1/20 0.56
JUN P05412 1/20 0.56
HCAR2 Q8TDS4 2/20 0.55
CA12 O43570 1/20 0.55
AKR1B10 O60218 1/20 0.55
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
ESR1 P03372 1/20 0.55
CA3 P07451 1/20 0.55
PKM P14618 1/20 0.55
TYR P14679 1/20 0.55
AKR1B1 P15121 1/20 0.55
CA4 P22748 1/20 0.55
CA6 P23280 1/20 0.55
DPP4 P27487 1/20 0.55
CA5A P35218 1/20 0.55
CA7 P43166 1/20 0.55
CA9 Q16790 1/20 0.55
ESR2 Q92731 1/20 0.55
CA14 Q9ULX7 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3633623 1.00 FOS (0.56) FOSJUNHCAR2CA12AKR1B10
Acrylic Acid SCHEMBL6862453 0.91 KDM4E (0.59) FOSJUNHCAR2CA12AKR1B10
Maleic Acid SCHEMBL8864871 0.90 ALDH1A1 (0.57) FOSJUNPKMMAPTALDH1A1
SCHEMBL175545 0.90 HCAR2 (0.65) HCAR2CA12AKR1B10CA1CA2
SCHEMBL7905993 0.90 FOS (0.66) FOSJUNHCAR2CA12AKR1B10
SCHEMBL5707299 0.90 HCAR2 (0.65) HCAR2CA12AKR1B10CA1CA2
SCHEMBL14107508 0.90 HCAR2 (0.65) HCAR2CA12AKR1B10CA1CA2
SCHEMBL80446 0.90 FOS (0.66) FOSJUNHCAR2CA12AKR1B10
SCHEMBL80447 0.90 FOS (0.66) FOSJUNHCAR2CA12AKR1B10
Acetic Acid SCHEMBL6697879 0.89 HCAR2 (0.59) HCAR2CA12AKR1B10CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2150133-A2 PRESERVATIVE DSM IP Assets B.V. (NL) 2010-02-10 EP disclosed
WO-2008149102-A2 PRESERVATIVE DSM FOOD SPECIALITIES B.V. (NL) 2008-12-11 WO disclosed